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Role of Acid-Suppressing Medications During a Sustained Outbreak of Salmonella Enteritidis Infection in a Long-Term Care Facility

Published online by Cambridge University Press:  02 January 2015

Anna Bowen*
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
Alexandra Newman
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia Wisconsin Division of Public Health, Madison, Wisconsin
Concepcion Estivariz
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
Norene Gilbertson
Affiliation:
Iron County Health Department, Hurley, Wisconsin
John Archer
Affiliation:
Wisconsin Division of Public Health, Madison, Wisconsin
Arjun Srinivasan
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
Michael Lynch
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
John Painter
Affiliation:
Centers for Disease Control and Prevention, Atlanta, Georgia
*
Enteric Diseases Epidemiology Branch, 1600 Clifton Road NE, MS A-38, Atlanta, GA30333 (aqb0@cdc.gov)

Abstract

During an insidious outbreak of salmonellosis in a long-term care facility, residents who were treated with acid-suppressing medications were 8 times more likely than other residents to develop Salmonella infection. Among vulnerable populations, the risks and benefits of acid-suppressing medications should be considered carefully before use.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2007 

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References

1. Stevenson, KB. Regional data set of infection rates for long-term care facilities: description of a valuable benchmarking tool. Am J Infect Control 1999;27:2026.Google Scholar
2. Top 300 prescriptions for 2005 by number of US prescriptions dispensed. Available at: http://www.rxlist.com/scriptymain/art.asp?articlekey=79509. Accessed October 18, 2006.Google Scholar
3. Wang, K, Lin, HJ, Perng, CL, et al. The effect of H2-receptor antagonist and proton pump inhibitor on microbial proliferation in the stomach. Hepatogastroenterology 2004;51:15401543.Google Scholar
4. Dial, S, Alrasadi, K, Manoukian, C, Huang, A, Menzies, D. Risk of Clostridium difficile diarrhea among hospital inpatients prescribed proton pump inhibitors: cohort and case-control studies. CMAJ 2004;171:3338.Google Scholar
5. Canani, RB, Cirillo, P, Roggero, P, et al. Therapy with gastric acidity inhibitors increases the risk of acute gastroenteritis and community-acquired pneumonia in children. Pediatrics 2006;117:e817820.Google Scholar
6. Laheij, RJ, Van Ijzendoorn, MC, Janssen, MJ, Jansen, JB. Gastric acid-suppressive therapy and community-acquired respiratory infections. Aliment Pharmacol Ther 2003;18:847851.Google Scholar
7. Neal, KR, Scott, HM, Slack, RC, Logan, RE Omeprazole as a risk factor for Campylobacter gastroenteritis: case-control study. BMJ 1996;312:414415.Google Scholar
8. Ho, JL, Shands, KN, Friedland, G, Eckind, P, Fraser, DW. An outbreak of type 4b Listeria monocytogenes infection involving patients from eight Boston hospitals. Arch Intern Med 1986;146:520524.Google Scholar
9. Smith, P, Rusnak, P. Infection prevention and control in the long-term care facility. Am J Infect Control 1997;25:488512.Google Scholar
10. Gordin, FM, Schultz, ME, Huber, RA, Gill, JA. Reduction in nosocomial transmission of drug-resistant bacteria after introduction of an alcohol-based handrub. Infect Control Hosp Epidemiol 2005;26:650653.Google Scholar