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Role of Coinfecting Strains in Recurrent Clostridium difficile Infection

Published online by Cambridge University Press:  30 August 2016

Janet Sun
Affiliation:
Infection Control, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York
Tracy Mc Millen
Affiliation:
Infection Control, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York Clinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
N. Esther Babady
Affiliation:
Clinical Microbiology Service, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Mini Kamboj*
Affiliation:
Infection Control, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York Department of Medicine, Weill Cornell Medical College, New York, New York
*
Address correspondence to Mini Kamboj, 1275 York Avenue, New York, NY 10065 (kambojm@mskcc.org).

Abstract

The contribution of mixed infection in recurrent Clostridium difficile infection (CDI) episodes is not known. Among paired isolates from 52 patients, mixed infection due to >1 toxigenic strain of C. difficile was identified in 8% of first episodes. Among recurrences, relapse from 1 or both co-infecting strains was uncommon; it was detected in a single case each.

Infect Control Hosp Epidemiol 2016;1481–1484

Type
Concise Communications
Copyright
© 2016 by The Society for Healthcare Epidemiology of America. All rights reserved 

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References

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