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Schistosoma japonicum infection in pregnant mice

Published online by Cambridge University Press:  11 April 2024

M. Bendixen ,
M.V. Johansen ,
J. Andreassen  and
P. Nansen
M. Bendixen*
Affiliation:
Danish Bilharziasis Laboratory, Jægersborg Allé 1D, DK-2920 Charlottenlund, Denmark Department of Population, Biology University of Copenhagen, Universitetsparken 15, DK-2100 Copenhagen, Denmark
M.V. Johansen
Affiliation:
Danish Bilharziasis Laboratory, Jægersborg Allé 1D, DK-2920 Charlottenlund, Denmark
J. Andreassen
Affiliation:
Department of Population, Biology University of Copenhagen, Universitetsparken 15, DK-2100 Copenhagen, Denmark
P. Nansen
Affiliation:
Danish Centre for Experimental Parasitology, Royal Veterinary and Agricultural University, Bülowsvej 13, DK-1870 Frederiksberg C, Denmark
*
*corresponding author: Fax: +45 77 32 77 33 E-mail: mb@bilharziasis.dk
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Abstract

Ten 1-week and ten 2-weeks pregnant female NMRI mice were experimentally exposed to 70 Schistosoma japonicum cercariae. Ten littermice from each group were examined for worms by perfusion 4, 6 and 8 weeks post infection. Although the mothers (n = 15) were found infected with 15.5 ± 13.4 worms at perfusion 6 and 7 weeks post infection, no worms were found in any of the examined littermice, as well as no detection of faecal or tissue eggs. Litter sizes did not differ from control groups and all littermice were healthy. The present study therefore suggests that congenital infection with S. japonicum does not occur in percutaneously infected mice and that infection of the mother during pregnancy does not seem to affect the offspring.

Type
Research Article
Information
Journal of Helminthology , Volume 73 , Issue 3 , March 1999 , pp. 277 - 278
Copyright
Copyright © Cambridge University Press 1999

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