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Variable infectivity of third-stage larvae of Brugia malayi

Published online by Cambridge University Press:  18 November 2009

Mark L. Eberhard  and
Robert C. Lowrie Jr
Mark L. Eberhard
Affiliation:
Department of Parasitology, Delta Regional Primate Research Center, Covington, Louisiana 70433, USA
Robert C. Lowrie Jr
Affiliation:
Department of Parasitology, Delta Regional Primate Research Center, Covington, Louisiana 70433, USA
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Abstract

Infectivity of third-stage larvae of Brugia malayi was assessed following intraperitoneal inoculation into jirds, Meriones unguiculatus. Larvae were of two ages and were derived from two sites in Aedes aegypti mosquitoes, i.e., specimens collected from the thorax 11 days after infection and from the head on day 14. Larvae from the thorax had just completed the second moult and measured 990 to 1100μm in length. Only 6% of these specimens developed to adult worms in jirds. Larvae that migrated to the head were 1400 to 1700 μm long on day 14 and, in contrast, 23% of the inocula developed to adult worms. This study establishes that all third-stage larvae, regardless of their age or location in the arthropod host, are potentially infective. However, pronounced physical maturation does seem to be accompanied by a marked increase in infectivity.

Type
Research Article
Information
Journal of Helminthology , Volume 59 , Issue 3 , September 1985 , pp. 283 - 285
Copyright
Copyright © Cambridge University Press 1985

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