Hostname: page-component-848d4c4894-nr4z6 Total loading time: 0 Render date: 2024-05-17T18:30:09.524Z Has data issue: false hasContentIssue false
  • English
  • Français

Adjuvant radiotherapy for primary mucosal malignant melanoma of the larynx

Published online by Cambridge University Press:  29 June 2007

L. Asare-Owusu ,
J. C. Shotton  and
J. B. Schofield
L. Asare-Owusu*
Affiliation:
ENT Department, Kent County Ophthalmic and Aural Hospital, Maidstone, Kent, UK.
J. C. Shotton
Affiliation:
ENT Department, Kent County Ophthalmic and Aural Hospital, Maidstone, Kent, UK.
J. B. Schofield
Affiliation:
Histopathology Department, Preston Hall Hospital, Aylesford, Kent, UK.
*
Address for correspondence: Mr L. Asare-Owusu, F.R.C.S.(Ed.), 55A Digby Crescent, London N4 2HS. e-mail: larry@doctors.org.uk
Get access Rights & Permissions [Opens in a new window]

Abstract

Primary mucosal malignant melanoma (PMML) of the larynx continues to be a rare entity. To date, there are few cases reported in the world literature consisting of mainly isolated case reports and literature reviews.

Traditionally believed to be radioresistant, we present a case of PMML of the right vocal fold managed with right cordectomy and adjuvant radiotherapy. The patient is well without any evidence of local recurrence or metastasis three years and four months from presentation.

Keywords

MelanomaLarynxSurgery, operativeRadiotherapy, adjuvant
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 10 , October 1999 , pp. 932 - 934
Copyright
Copyright © JLO (1984) Limited 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Berthelsen, A., Andersen, A. P., Jensen, T. S., Hansen, H. S. (1984) Melanomas of the mucosa in the oral cavity and upper respiratory passages. Cancer 54: 907–912.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Blatchford, S. J., Koopmann, C. F., Coulthard, S. W. (1986) Mucosal melanoma of the head and neck. Laryngoscope 96: 929–934.CrossRefGoogle ScholarPubMed
Conley, J. (1989) Melanomas of the mucous membranes of the head and neck. Laryngoscope 99: 1248–1253.CrossRefGoogle ScholarPubMed
Cremonesi, G. (1956) Su un eccezionale reperto di sarcoma melanotico primitivo della laringe. Minerva Otorrinolaringo 6: 333–340.Google Scholar
Duwel, V., Michielssen, P. (1996) Primary malignant melanoma of the larynx. A case report. Acta Oto-Rhino-Laryngologica Belgica 50: 47–49.Google ScholarPubMed
El-Barbary, A. E., Fouad, H. A., El-Sayed, A. F. (1968) Malignant melanoma involving the larynx report of two cases. Annals of Otology 77: 338–343.Google Scholar
Gray, R. F. (1992) Surgical anatomy. In Synopsis of Otolaryngology. 5th Edition. (Hawthorne, M., ed.). Butterworth-Heinemann Ltd., Oxford, p 428.Google Scholar
Hussein, S. S. M., Whitehead, E. (1989) Malignant melanoma of larynx. Journal of Laryngology and Otology 103: 533–536.CrossRefGoogle Scholar
Karagiannidis, K., Noussios, G., Sakellariou, T., Kontzoglou, G., Mantziaris, V., Preponis, C. (1998) Primary laryngeal melanoma. Journal of Otolaryngology 27(2): 104–106.Google ScholarPubMed
Kim, H., Park, C. I. (1982) Primary malignant laryngeal melanoma: report of a case with review of literature. Yonsei Medical Journal 23: 118–122.CrossRefGoogle ScholarPubMed
Lorenz, E. (1979) Das maligne melanom des kehlkopfes. HNO 27: 275–277.Google Scholar
Loughead, J. R., Bushnell, J. (1954) Metastasis of malignant tumours to the larynx. Laryngoscope 60: 50–52.CrossRefGoogle Scholar
Mattavelli, F., Di Palma, S., Guzzo, M. (1995) Primary mucosal malignant melanoma of the larynx: case report and review of the literature. Tumori 81(6): 460–463.CrossRefGoogle ScholarPubMed
Panje, W. R., Moran, W. J. (1986) Melanoma of the upper aerodigestive tract: a review of 21 cases. Head and Surgery 8: 309–312.CrossRefGoogle ScholarPubMed
Reuter, V. E., Woodruff, J. M. (1986) Melanoma of the larynx. Laryngoscope 96(4): 389–393.CrossRefGoogle ScholarPubMed
Schmidt-Ullrich, R. K., Johnson, C. R. (1996) Role of radiotherapy and hyperthermia in the management of malignant melanoma. Seminars in Surgical Oncology 12: 407–415.3.0.CO;2-E>CrossRefGoogle ScholarPubMed
Shah, J. P., Huvos, A. G., Strong, E. W. (1977) Mucosal melanomas of the head and neck. American Journal of Surgery 26: 381–385.Google Scholar
Trotti, A., Peters, L. J. (1993) Role of radiotherapy in the primary management of mucosal melanoma of head and neck. Seminars in Surgical Oncology 9: 246–250.CrossRefGoogle Scholar
Wenig, B. M. (1995) Laryngeal mucosal malignant melanoma. A clinicopathologic, immunohistochemical and ultrastructural study of four patients and a review of the literature. Cancer 75(7): 1568–1577.3.0.CO;2-M>CrossRefGoogle Scholar