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Factors associated with the development of paediatric chronic otitis media by age nine: a prospective longitudinal cohort study of 6560 children

Published online by Cambridge University Press:  19 November 2020

P J Clamp ,
K De-Loyde ,
A R Maw ,
S Gregory ,
J Golding  and
A Hall
P J Clamp*
Affiliation:
Department of ENT, University Hospitals Bristol NHS Foundation Trust, Bristol, UK School of Social and Community Medicine, University of Bristol, UK
K De-Loyde
Affiliation:
School of Social and Community Medicine, University of Bristol, UK
A R Maw
Affiliation:
School of Social and Community Medicine, University of Bristol, UK
S Gregory
Affiliation:
School of Social and Community Medicine, University of Bristol, UK
J Golding
Affiliation:
School of Social and Community Medicine, University of Bristol, UK
A Hall
Affiliation:
Children's Hearing Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, UK Life and Health Sciences, Aston University, Birmingham, UK
*
Author for correspondence: Mr Philip J Clamp, Department of ENT, St. Michael Hospital, University Hospitals Bristol, Southwell Street, BristolBS2 8EG, UK E-mail: philip.clamp@uhbristol.nhs.uk
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Abstract

Objective

This study aimed to analyse social, health and environmental factors associated with the development of chronic otitis media by age nine.

Method

This was a prospective, longitudinal, birth cohort study of 6560 children, reviewed at age nine. Chronic otitis media defined as previous surgical history or video-otoscopic changes of tympanic membrane retraction, perforation or cholesteatoma. Non-affected children were used as the control group.

Results

Univariate analysis demonstrated an association between chronic otitis media and otorrhoea, snoring, grommet insertion, adenoidectomy, tonsillectomy, hearing loss, abnormal tympanograms and preterm birth. Multivariate analysis suggests many of these factors may be interrelated.

Conclusion

The association between chronic otitis media and otorrhoea, abnormal tympanograms and grommets supports the role of the Eustachian tube and otitis media (with effusion or acute) in the pathogenesis of chronic otitis media. The role of snoring, adenoidectomy and tonsillectomy is unclear. Associations suggested by previous studies (sex, socioeconomic group, parental smoking, maternal education, childcare, crowding and siblings) were not found to be significant predictors in this analysis.

Keywords

Otitis MediaCholesteatomaTympanic Membrane PerforationPediatricsRisk FactorsCohort StudiesHearing LossOtological Surgical ProceduresMiddle Ear VentilationSnoringTonsillectomyAdenoidectomy
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 11 , November 2020 , pp. 998 - 1009
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Mr P J Clamp takes responsibility for the integrity of the content of the paper

Presented at British Academic Conference in Otolaryngology International, 4–6 July 2018, Manchester, UK.

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