Hostname: page-component-848d4c4894-x24gv Total loading time: 0 Render date: 2024-05-10T13:11:52.332Z Has data issue: false hasContentIssue false
  • English
  • Français

Hyalinizing clear cell carcinoma of the nasopharynx operated by trans-oral and trans-palatal approach

Published online by Cambridge University Press:  23 February 2015

T Nakashima ,
R Yasumatsu ,
M Yamauchi ,
S Toh ,
T Nakano ,
H Yamamoto  and
S Komune
T Nakashima*
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
R Yasumatsu
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
M Yamauchi
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
S Toh
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
T Nakano
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
H Yamamoto
Affiliation:
Department of Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
S Komune
Affiliation:
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
*
Address for correspondence: T Nakashima, Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medical Sciences, Kyushu University, 3–1–1 Maidashi, Higashiku, Fukuoka 812–8582, Japan E-mail: nakatora@qent.med.kyushu-u.ac.jp
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

Hyalinizing clear cell carcinoma is a rare minor salivary gland neoplasm. The treatment of choice is surgical resection with or without post-operative radiotherapy. This tumour often demonstrates a good prognosis.

Case report:

We report a case of hyalinizing clear cell carcinoma arising in the nasopharynx. A 27-year-old female presented with progressive hearing disturbance and tinnitus. On examination, an expansile mass was observed in her nasopharynx. Biopsy was performed and the pathology results returned as clear cell carcinoma.

Results and conclusion:

Surgical resection was performed trans-orally accompanied by trans-palatal approach. She has no recurrence during more than two years of follow up.

Keywords

Hyalinizing Clear-cell CarcinomaSalivary GlandTrans-palatal Approach
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 129 , Issue S2 , March 2015 , pp. S95 - S97
Copyright
Copyright © JLO (1984) Limited 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Balakrishnan, R, Nayak, DR, Pillai, S, Rao, L. Hyalinizing clear cell carcinoma of the base of the tongue. J Laryngol Otol 2002;116:851–3Google Scholar
2Milchgrub, S, Gnepp, DR, Vuitch, F, Delgado, R, Albores-Saavedra, J. Hyalinizing clear cell carcinoma of salivary gland. Am J Surg Pathol 1994;18:74–82CrossRefGoogle ScholarPubMed
3Cheng, LH, Lin, YS, Lee, JC. Primary clear cell carcinoma of the nasopharynx. Otolaryngol Head Neck Surg 2008;139:592–3CrossRefGoogle ScholarPubMed
4O'Sullivan-Mejia, ED, Massey, HD, Faquin, WC, Powers, CN. Hyalinizing clear cell carcinoma: report of eight cases and a review of literature. Head Neck Pathol 2009;3:179–85Google Scholar
5Antonescu, CR, Katabi, N, Zhang, L, Sung, YS, Seethala, RR, Jordan, RC et al. EWSR1–ATF1 fusion is a novel and consistent finding in hyalinizing clear-cell carcinoma of salivary gland. Genes Chromosomes Cancer 2011;50:559–70CrossRefGoogle ScholarPubMed
6Menezes, AH. Surgical approaches: postoperative care and complications ‘transoral–transpalatopharyngeal approach to the craniocervical junction’. Childs Nerv Syst 2008;24:1187–93CrossRefGoogle Scholar
7Hijjawi, SB, Abdullah, SE, Abdelhadi, K, Eyzaguirre, E, Willis, M, Abdulla, NE. Hyalinizing clear cell carcinoma of the tonsil and its treatment. Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114:e32–6Google Scholar
8Solar, AA, Schmidt, BL, Jordan, RC. Hyalinizing clear cell carcinoma: case series and comprehensive review of the literature. Cancer 2009;115:75–83CrossRefGoogle ScholarPubMed
9Su, HK, Wang, BY, Mannan, AA, Dewey, EH, Alpert, EH, Dos Reis, LL et al. Very delayed cervical lymph node metastases from hyalinizing clear cell carcinoma: report of two cases. Head Neck 2014 in Press.Google Scholar