Hostname: page-component-848d4c4894-x24gv Total loading time: 0 Render date: 2024-05-21T17:17:33.667Z Has data issue: false hasContentIssue false
  • English
  • Français

Multiple myeloma presenting with external ear canal mass

Published online by Cambridge University Press:  29 June 2007

D. Quinodoz ,
P. Dulguerov ,
A.-M. Kurt ,
D. Ruefenacht ,
R. Abele ,
A. S. Allal  and
P. Montandon
D. Quinodoz
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneya 14, Switzerland
P. Dulguerov*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneya 14, Switzerland
A.-M. Kurt
Affiliation:
Department of Otolaryngology and Pathology, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneya 14, Switzerland
D. Ruefenacht
Affiliation:
Department of Otolaryngology and Radiology, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneya 14, Switzerland
R. Abele
Affiliation:
Department of Otolaryngology and Medicine, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneya 14, Switzerland
A. S. Allal
Affiliation:
Department of Otolaryngology and Radiology, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneya 14, Switzerland
P. Montandon
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneya 14, Switzerland
*
Address for correspondence: Pavel Dulguerov, M.D., Department of Otolaryngology, Head and Neck Surgery, University Canton Hospital, 24 Rue Micheli-du-Crest, 1211 Geneva 14, Switzerland. Fax: (4122) 372 82 40 e-mail: Pavel.Dulguerov@hcuge.ch
Get access Rights & Permissions [Opens in a new window]

Abstract

The manifestations of multiple myeloma are protean and related to bony osteolytic lesions, and to medullar and renal insufficiency. We report a patient who presented with otalgia as the inaugural symptom of multiple myeloma. Local irradiation combined with systemic chemotherapy led to the disappearance of the temporal bone mass and the accompanying symptoms. To date, 24 months after the diagnosis, the patient is still in remission.

The literature on otological involvement in multiple myeloma is reviewed. Symptoms are non-specific and include hearing loss, tinnitus, dizziness, facial paralysis, and otalgia. The diagnosis of multiple myeloma should be considered in the presence of a temporal bone mass.

Keywords

EarMultiple myelomaPainDrug therapyRadiotherapy
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 5 , May 1998 , pp. 469 - 471
Copyright
Copyright © JLO (1984) Limited 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abemayor, E., Canalis, R. F., Greenberg, P., Wortham, D. G., Rowland, J. P., Sun, N. C. J. (1988) Plasma cell tumors of the head and neck. Journal of Otolaryngology 17: 376–381.Google ScholarPubMed
Alexian, R., Dimopulos, M. (1994) The treatment of multiple myeloma. New England Journal of Medicine 330: 484–489.Google Scholar
Barlogie, B. (1995) Plasma cell myeloma. In Williams Hematology. 5th Edition. (Beutler, E., Lichtman, M. A., Coller, B. S., Kipps, T. J., eds.), McGraw-Hill, New York, pp 1109–1123.Google Scholar
Bataille, R., Harousseau, J. L. (1997) Multiple myeloma. New England Journal of Medicine 336: 1657–1664.CrossRefGoogle ScholarPubMed
Chevalier, X., Wrona, N. N., Larget-Piet, B. (1992) Vestibular syndrome in multiple myeloma: role of magnetic resonance imaging. Clinical Rheumatology 11: 405–407.CrossRefGoogle ScholarPubMed
Funakubo, T., Kikuchi, A. (1994) A case of myeloma with facial palsy. Ada Otolaryngologica (Suppl 511): 200–203.CrossRefGoogle ScholarPubMed
Hyams, V. F. (1987) Pathology of tumors of the ear. In Comprehensive Management of Head and Neck Tumor. (Thawley, S. E., Panje, W. R., eds.), W. B. Saunders, Philadelphia, pp 168–193.Google Scholar
Jackler, R. K., Parker, D. A. (1992) Radiographic differential diagnosis of petrous apex lesions. American Journal of Otology 13: 561–574.Google ScholarPubMed
Keay, D. (1988) Total bilateral hearing loss as a complication of myeloma. Journal of Laryngology and Otology 102: 357–358.CrossRefGoogle ScholarPubMed
Kemink, J. L., Graham, M. D., Gebarski, S. S. (1993) Surgery of the temporal bone neoplasms. In Otolaryngology – Head and Neck Surgery. 2nd Edition. (Cummings, C. W., Fredrickson, J. M., Harker, L. A., Krause, C. J., Schuller, D. E., eds.), Mosby Year Book, Inc., St Louis, pp 3353–3370.Google Scholar
Lavine, R. F., Mattucci, K. F., Merton, C. W. (1979) Multiple myeloma of the temporal bone. Ear Nose and Throat Journal 58: 210–213.Google Scholar
Li, W., Schachern, P. A., Morizono, T., Paparella, M. M. (1994) The temporal bone in multiple myeloma. Laryngoscope 104: 675–680.CrossRefGoogle ScholarPubMed
Marks, P. V., Brookes, G. B. (1985) Myelomatosis presenting as an isolated lesion in the mastoid. Journal of Laryngology and Otology 99: 903–906.CrossRefGoogle ScholarPubMed
Schuknecht, H. F. (1993) Pathology of the Ear. 2nd Edition. Harvard University Press, Cambridge, p 498.Google Scholar
Selby, P., Gore, M. (1995) Myeloma and other plasma cell malignancies. In Oxford Textbook of Oncology. (Peckham, M., Pinedo, H. M., Veronesi, U., eds.), Oxford University Press, Oxford, pp 1852–1878.Google Scholar
Shone, G. R. (1985) Facial palsy due to myeloma of the temporal bone. Journal of Laryngology and Otology 99: 907–908.Google Scholar