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Scintigraphic evaluation of glomus tumours

Published online by Cambridge University Press:  29 June 2007

T. A. Rockall ,
J. C. Watkinson ,
S. E. M. Clark  and
E. E. Douek
T. A. Rockall*
Affiliation:
Departments of Otolaryngology, Guy's Hospital, London.
J. C. Watkinson
Affiliation:
Departments of Otolaryngology, Guy's Hospital, London. Departments of Nuclear Medicine, Guy's Hospital, London.
S. E. M. Clark
Affiliation:
Departments of Nuclear Medicine, Guy's Hospital, London.
E. E. Douek
Affiliation:
Departments of Otolaryngology, Guy's Hospital, London.
*
Dr T. A. Rockall, Department of Otolaryngology, Guys Hospital, St Thomas' Street, London SE1 9RT.
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Abstract

The current investigations of choice for a suspected glomus tumour are either direct or indirect angiography to include digital subtraction followed by computerized tomography (CT) or magnetic resonance imaging (MRI) or, if available, CT and MRI with gadolinium alone. Although these modalities confirm the diagnosis and give anatomical information to facilitate accurate staging, they do not provide functional data. The use of radionuclide scintigraphy can add an extra physiological dimension to glomus tumour imaging.

Iodine-131/123 metaiodobenzylguanidine (MIBG) is a tumour imaging agent which has been used to diagnose head and neck neuroendocrine tumours to include paragangliomata and medullary carcinoma of the thyroid (MCT). However, it is expensive and the new head and neck tumour imaging agent technetium-99 m (Tc99m) (v) dimercaptosuccinic acid (DMSA) has superceded it as the imaging agent of choice to evaluate MCT. We report a patient with a glomus jugulare tumour which was evaluated with I131/I123-MIBG and Tc99m (v) DMSA. The tumour was functional and is the first reported case exhibiting positive accumulation of both I131-MIBG and Tc99m (v) DMSA. The patient was subsequently treated with a therapeutic dose of I131-MIBG. The significance of these results is discussed.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 104 , Issue 1 , January 1990 , pp. 33 - 36
Copyright
Copyright © JLO (1984) Limited 1990

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