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  • Cited by 2
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    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Cala, Cather M. Kole, Lauren and Sami, Naveed 2015. Bilateral Sensorineural Hearing Loss and Polyneuropathy in a Patient with Sweet’s Syndrome. Case Reports in Otolaryngology, Vol. 2015, p. 1.

    Anzalone, Charles L. and Cohen, Philip R. 2013. Acute febrile neutrophilic dermatosis (Sweetʼs syndrome). Current Opinion in Hematology, Vol. 20, Issue. 1, p. 26.


Sweet's disease and profound, bilateral, sensorineural hearing loss

  • S Cheng (a1) and M da Cruz (a1)
  • DOI:
  • Published online: 20 October 2009

We report a case of Sweet's disease associated with rapid, profound loss of hearing, against a background of progressive, bilateral, sensorineural hearing loss.


The clinical features were indistinguishable from those of immune-mediated inner ear disease. Establishment of a definitive diagnosis was a challenge due to the absence of a reliable diagnostic test. The patient was unresponsive to extensive immunosuppressive therapy and subsequently underwent cochlear implantation, with good hearing outcomes.


Profound, bilateral, sensorineural hearing loss in the context of Sweet's disease may be related to the underlying immunological aetiology. Cochlear implantation can successfully restore hearing when immunotherapy fails.

Corresponding author
Address for correspondence: Prof Melville da Cruz, Department of Surgery, Westmead Hospital, Hawkesbury Road, Westmead, NSW, Australia2145. Fax: +61 2 98937440 E-mail:
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1RD Sweet . An acute febrile neutrophilic dermatosis. Br J Dermatol 1964;76:349–56

2PR Cohen . Sweet's syndrome – a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis 2007;2:128

3PR Cohen , R Kurzrock . Sweet's syndrome revisited: a review of disease concepts. Int J Dermatol 2003;42:761–78

4DB Pharis , D Cerenko , SW Caughman . Sweet's syndrome in a patient with idiopathic progressive bilateral sensorineural hearing loss. J Am Acad Dermatol 2000;42:932–5

5T Wada , H Sato , S Izumi , Y Kubota , Y Ueki , T Fujisaki Neuro-Sweet's disease in a patient with bilateral recurrent acute sensorineural hearing loss. Audiol Jpn 2006;49:254–9

6BF McCabe . Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol 1979;88:585–9

7JP Harris , P Sharp . Inner ear autoantibodies in patients with rapidly progressive sensorineural hearing loss. Laryngoscope 1990;100:516–24

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The Journal of Laryngology & Otology
  • ISSN: 0022-2151
  • EISSN: 1748-5460
  • URL: /core/journals/journal-of-laryngology-and-otology
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