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Cryo-electron microscopy of influenza vaccine nanoparticles indicates full occupancy of displayed epitopes is facilitated by particle design

Published online by Cambridge University Press:  25 July 2016

John R. Gallagher
Affiliation:
Structural Informatics Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
Audray K. Harris
Affiliation:
Structural Informatics Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA

Abstract

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Type
Abstract
Copyright
© Microscopy Society of America 2016 

References

Reference:

[1] Maity, P.C., et al., Biochim Biophys Acta 1853 (2015). p. 830840.CrossRefGoogle Scholar
[2] Smith, D.M., et al., Nat Rev Immunol 13 (2013). p. 592605.Google Scholar
[3] Yassine, H.M., et al., Nat Med 21 (2015). p. 10651070.Google Scholar
[4] The authors acknowledge support from NIH/NIAID, and Vinod Nair and Elizabeth Fischer at the NIAID Rocky Mountain Labs Research Technologies Branch for cryo-electron microscopy data collection.Google Scholar