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Utilization of Optical Polarization Microscopy in the Study of Sorption Characteristics of Wound Dressing Host Materials

Published online by Cambridge University Press:  24 February 2014

Miha Devetak ,
Zdenka Peršin ,
Karin Stana-Kleinschek  and
Uroš Maver Open the ORCID record for Uroš Maver [Opens in a new window]
Miha Devetak*
Affiliation:
CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia
Zdenka Peršin
Affiliation:
CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia Faculty of Mechanical Engineering, Laboratory for Characterisation and Processing of Polymers, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia Member of Centre for Open Innovations and Research UM (CORE@UM)
Karin Stana-Kleinschek
Affiliation:
CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia Faculty of Mechanical Engineering, Laboratory for Characterisation and Processing of Polymers, University of Maribor, Smetanova 17, SI-2000 Maribor, Slovenia Member of Centre for Open Innovations and Research UM (CORE@UM)
Uroš Maver
Affiliation:
CE PoliMaT, Tehnološki park 24, SI-1000 Ljubljana, Slovenia Member of Centre for Open Innovations and Research UM (CORE@UM) Faculty of Medicine, University of Maribor, Slomškov Trg 15, SI-2000 Maribor, Slovenia
*
*Corresponding author. miha.devetak@polimat.si
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Abstract

Polarization microscopy was used for evaluation of kinetics of diclofenac sorption in three different wound dressing materials. The sorption kinetics can be evaluated by radii change and intensity of the light traveling through the fiber. The most frequently used host materials for drugs in wound dressings are alginate, polyesters such as polyethylene terephthalate, and viscose. We studied sorption of diclofenac as an example drug. Effective, but rather simple in vitro simulation of diclofenac sorption gives insight into the applicability of the mentioned materials for development of wound healing materials.

Keywords

polarization microscopyalginatePETviscosediclofenacsorption
Type
Biological Applications
Information
Microscopy and Microanalysis , Volume 20 , Issue 2 , April 2014 , pp. 561 - 565
Copyright
© Microscopy Society of America 2014 

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