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Biomimetic Spinning of Recombinant Silk Proteins

Published online by Cambridge University Press:  31 January 2011

David Keerl
Affiliation:
david.keerl@bm.uni-bayreuth.de, Universitaet Bayreuth, Biomaterialien, Bayreuth, Germany
John George Hardy
Affiliation:
john.hardy@bm.uni-bayreuth.de, Universitaet Bayreuth, Biomaterialien, Bayreuth, Germany
Thomas Scheibel
Affiliation:
Thomas.Scheibel@bm.uni-bayreuth.de, Universitaet Bayreuth, Biomaterialien, Bayreuth, Germany
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Abstract

In the past, we have successfully designed and produced a variety of engineered spider silk-like proteins (eADF3 and eADF4) based upon the primary sequence of the natural dragline proteins ADF3 and ADF4 from the spider Araneus diadematus [1]. Genetically engineered spider silk proteins can be modified at the molecular level to optimize the biochemical and mechanical properties of the final product. Although engineered spider silk proteins can be processed into fibers using different spinning methods, our group is interested in the technical realization of a biomimetic approach. Here, we present an overview over our biomimetic fiber production process.

Type
Research Article
Copyright
Copyright © Materials Research Society 2010

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