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Controlling Cell Growth by Nanoparticles

Published online by Cambridge University Press:  01 February 2011

Sergiy Zankovych
Affiliation:
s.zankovych@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany, ++ 49 3641 947736, ++ 49 3641 947732
Joerg Bossert
Affiliation:
p5jobo@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
Ines Thiele
Affiliation:
ines.thiele@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
Klaus D. Jandt
Affiliation:
k.jandt@uni-jena.de, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
Liga Berzina-Cimdina
Affiliation:
liga@ktf.rtu,lv, Friedrich-Schiller-University Jena, Institute for Materials Science and Technology, Loebdergraben 32, Jena, 07749, Germany
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Abstract

We report preliminary results of using nanoparticles to control cell attachment and growth. We present the way to create titanium surfaces with different roughness in a rage between 2 nm and 117 nm by using nanoparticles as a superficial layer and varying the evaporation parameters. We examined cell proliferation on titanium substrates with increased surface roughness compared to smooth titanium surface. We used nanoparticles to create a micrometer-sized lateral layout onto substrates preliminary structured by microcontact printing. We demonstrate controlled cell growth on substrates laterally structured with nanoparticles.

Type
Research Article
Copyright
Copyright © Materials Research Society 2007

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References

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