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Rheology of Sodium Hyaluronate Solutions and Relevance to their Use as Medical Implants

Published online by Cambridge University Press:  26 February 2011

Dale P. Devore ,
Sandra A. Loftus  and
B. S. MedChem
Dale P. Devore
Affiliation:
Products, Inc., Acton, MA 01720
Sandra A. Loftus
Affiliation:
Products, Inc., Acton, MA 01720
B. S. MedChem
Affiliation:
Products, Inc., Acton, MA 01720
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Extract

Hyaluronic acid is a high molecular weight, linear polysaccharide composed of repeating subunits of glucuronic acid and N-acetylglucosamine. The structure is shown in figure 1. In vertebrates, the polymer is widely distributed through all connective tissue and has been implicated in cell-cell interaction, cell matrix adhesion, cell mobility and extracellular matrix organization (1,2). NaHA is an important tissue lubricant (3,4) and has been shown to exert a facilitating influence on wound repair (5).

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 110: Symposium M – Biomedical Materials and Devices , 1987 , 455
Copyright
Copyright © Materials Research Society 1988

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References

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