Recent medical literature has pointed out the health hazards associated with industrial wastes and by-products; however, little emphasis has been placed on the dangers inherent in scientific laboratories. These hazards range from direct contact with toxic chemicals and vapors to exposure to ionizing radiation. The damage may be acute or chronic; the effects temporary or residual. What follows is a summary of the common hazards, the basic management of laboratory trauma, and guidelines to prevent injury. The individual preceding chapters also contain safety information relative to the specific lab techniques discussed.