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Oxygen via the Peritoneum

Published online by Cambridge University Press:  28 June 2012

N.S. Faithfull
Affiliation:
Departments of Anesthesia, Erasmus University, Rotterdam, The Netherlands
P.J. Salt
Affiliation:
Departments of Anesthesia, University of Birmingham, United Kingdom
J. Klein
Affiliation:
Departments of Anesthesia, Erasmus University, Rotterdam, The Netherlands
H. Soini
Affiliation:
Departments of Anesthesia, University of Birmingham, United Kingdom
H. van der Zee
Affiliation:
Departments of Anesthesia, Albany Medical College, Albany, New York, U.S.A.
W. Erdmann
Affiliation:
Departments of Anesthesia, Erasmus University, Rotterdam, The Netherlands

Extract

Perfluorochemicals (PFCs), which are also known as fluorocarbons or perfluorocarbons, are chemical substances having a high solubility for respiratory gases. At 37 degrees Centigrade pure PFCs can dissolve very large quantities of oxygen and in some instances this may amount to as much as 50 volumes %. These substances are however immiscible with blood and if introduced into the circulation in an unmodified form could cause embolic phenomena. In order to be of use as oxygen carrying blood substitutes, they are therefore emulsified in a solution containing glucose, electrolytes and an osmotic agent.

Type
Clinical Topics
Copyright
Copyright © World Association for Disaster and Emergency Medicine 1987

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