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Intestinal gene expression in response to zinc oxide and rearing environment in the ETEC-challenged weaned piglet

Published online by Cambridge University Press:  23 November 2017

H. Sargeant ,
M-A. Shaw  and
H. Miller
H. Sargeant*
Affiliation:
University of Leeds, Leeds, United Kingdom
M-A. Shaw
Affiliation:
University of Leeds, Leeds, United Kingdom
H. Miller
Affiliation:
University of Leeds, Leeds, United Kingdom
*
Email:bgy2hs@leeds.ac.uk
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Extract

Enterotoxigenic Escherichia coli (ETEC) K88 is a common cause of post-weaning scours in piglets. Supplementation of the post-weaning diet with pharmacological levels of zinc oxide reduces the incidence and severity of scours (Carlson et al 2004), in particular that caused by ETEC K88 (Owusu-Asiedu et al. 2003). Piglets reared outdoors pre-weaning also perform better post-weaning than those reared indoors, with an increased growth rate (Miller et al, 2007). The objective of this study was to identify genes that are differentially expressed in the small intestine of the ETEC-challenged piglet in response to dietary ZnO supplementation and outdoor rearing, to increase understanding of the mechanism by which these factors exert their effects.

Type
Theatre Presentations
Information
Proceedings of the British Society of Animal Science , Volume 2008 , 2008 , pp. 90
Copyright
Copyright © The British Society of Animal Science 2008

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References

Carlson, D, Poulsen, HD, Vestergaard, M. 2004. Journal of Animal Physiology and Animal Nutrition 88(9-10): 332 Google Scholar
Owusu-Asiedu, A, Nyachoti, CM, Marquardt, RR. 2003. Journal of Animal Science 81(7): 1790–1798.Google Scholar
Miller, H.M., Carroll, S.M., Reynolds, F.H. and Slade, R.D. 2007. BSAS proceedings 2007Google Scholar
Slade, RD, Carroll, S., Reynolds, F., White, K., Wellock, I., Kyriasakis, I and Miller, HM. 2008. BSAS Proceedings. 88 Google Scholar