Tozzi, Leonardo Doolin, Kelly Farrel, Chloe Joseph, Sojo O’Keane, Veronica and Frodl, Thomas 2017. Functional magnetic resonance imaging correlates of emotion recognition and voluntary attentional regulation in depression: A generalized psycho-physiological interaction study. Journal of Affective Disorders, Vol. 208, p. 535.
Bertocci, Michele A. Bebko, Genna Dwojak, Amanda Iyengar, Satish Ladouceur, Cecile D. Fournier, Jay C. Versace, Amelia Perlman, Susan B. Almeida, Jorge R.C. Travis, Michael J. Gill, Mary Kay Bonar, Lisa Schirda, Claudiu Diwadkar, Vaibhav A. Sunshine, Jeffrey L. Holland, Scott K. Kowatch, Robert A. Birmaher, Boris Axelson, David Horwitz, Sarah M. Frazier, Thomas Arnold, L. Eugene Fristad, Mary A. Youngstrom, Eric A. Findling, Robert L. and Phillips, Mary L. 2016. Longitudinal Relationships Among Activity in Attention Redirection Neural Circuitry and Symptom Severity in Youth. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging,
Chen, Guangxiang Hu, Xinyu Li, Lei Huang, Xiaoqi Lui, Su Kuang, Weihong Ai, Hua Bi, Feng Gu, Zhongwei and Gong, Qiyong 2016. Disorganization of white matter architecture in major depressive disorder: a meta-analysis of diffusion tensor imaging with tract-based spatial statistics. Scientific Reports, Vol. 6, p. 21825.
Eack, Shaun M. Wojtalik, Jessica A. Barb, Scott M. Newhill, Christina E. Keshavan, Matcheri S. Phillips, Mary L. and Pavlova, Marina A. 2016. Fronto-Limbic Brain Dysfunction during the Regulation of Emotion in Schizophrenia. PLOS ONE, Vol. 11, Issue. 3, p. e0149297.
Goya-Maldonado, Roberto Brodmann, Katja Keil, Maria Trost, Sarah Dechent, Peter and Gruber, Oliver 2016. Differentiating unipolar and bipolar depression by alterations in large-scale brain networks. Human Brain Mapping, Vol. 37, Issue. 2, p. 808.
He, Hao Yu, Qingbao Du, Yuhui Vergara, Victor Victor, Teresa A. Drevets, Wayne C. Savitz, Jonathan B. Jiang, Tianzi Sui, Jing and Calhoun, Vince D. 2016. Resting-state functional network connectivity in prefrontal regions differs between unmedicated patients with bipolar and major depressive disorders. Journal of Affective Disorders, Vol. 190, p. 483.
Laidi, Charles and Houenou, Josselin 2016. Brain functional effects of psychopharmacological treatments in bipolar disorder. European Neuropsychopharmacology, Vol. 26, Issue. 11, p. 1695.
Li, Hui Xu, Haiyun Zhang, Yinnan Guan, Jitian Zhang, Jie Xu, Chongtao Shen, Zhiwei Xiao, Bo Liang, Chunlian Chen, Kaiyuan Zhang, Jinling and Wu, Renhua 2016. Differential neurometabolite alterations in brains of medication-free individuals with bipolar disorder and those with unipolar depression: a two-dimensional proton magnetic resonance spectroscopy study. Bipolar Disorders, Vol. 18, Issue. 7, p. 583.
Sharma, Anup Satterthwaite, Theodore D. Vandekar, Lillie Katchmar, Natalie Daldal, Aylin Ruparel, Kosha Elliott, Mark A. Baldassano, Claudia Thase, Michael E. Gur, Raquel E. Kable, Joseph W. and Wolf, Daniel H. 2016. Divergent relationship of depression severity to social reward responses among patients with bipolar versus unipolar depression. Psychiatry Research: Neuroimaging, Vol. 254, p. 18.
Vogt, Brent A. 2016. Midcingulate cortex: Structure, connections, homologies, functions and diseases. Journal of Chemical Neuroanatomy, Vol. 74, p. 28.
Wolf, Robert Christian Nolte, Henrike Maria Hirjak, Dusan Hofer, Stefan Seidl, Ulrich Depping, Malte Sebastian Stieltjes, Bram Maier-Hein, Klaus Sambataro, Fabio and Thomann, Philipp Arthur 2016. Structural network changes in patients with major depression and schizophrenia treated with electroconvulsive therapy. European Neuropsychopharmacology, Vol. 26, Issue. 9, p. 1465.
Brooks, J. O. Vizueta, N. Penfold, C. Townsend, J. D. Bookheimer, S. Y. and Altshuler, L. L. 2015. Prefrontal hypoactivation during working memory in bipolar II depression. Psychological Medicine, Vol. 45, Issue. 08, p. 1731.
Caseras, Xavier Murphy, Kevin Lawrence, Natalia S Fuentes-Claramonte, Paola Watts, Jessica Jones, Derek K and Phillips, Mary L 2015. Emotion regulation deficits in euthymic bipolar I versus bipolar II disorder: a functional and diffusion-tensor imaging study. Bipolar Disorders, Vol. 17, Issue. 5, p. 461.
Kanske, P Schönfelder, S Forneck, J and Wessa, M 2015. Impaired regulation of emotion: neural correlates of reappraisal and distraction in bipolar disorder and unaffected relatives. Translational Psychiatry, Vol. 5, Issue. 1, p. e497.
Ryan, Kelly A. Dawson, Erica L. Kassel, Michelle T. Weldon, Anne L. Marshall, David F. Meyers, Kortni K. Gabriel, Laura B. Vederman, Aaron C. Weisenbach, Sara L. McInnis, Melvin G. Zubieta, Jon-Kar and Langenecker, Scott A. 2015. Shared dimensions of performance and activation dysfunction in cognitive control in females with mood disorders. Brain, Vol. 138, Issue. 5, p. 1424.
Varga, Mihai Visu-Petra, George Miclea, Mircea Visu-Petra, Laura and Urgesi, Cosimo 2015. The “Good Cop, Bad Cop” Effect in the RT-Based Concealed Information Test: Exploring the Effect of Emotional Expressions Displayed by a Virtual Investigator. PLOS ONE, Vol. 10, Issue. 2, p. e0116087.
Wang, Xiu-Li Du, Ming-Ying Chen, Tao-Lin Chen, Zi-Qi Huang, Xiao-Qi Luo, Ya Zhao, You-Jin Kumar, Poornima and Gong, Qi-Yong 2015. Neural correlates during working memory processing in major depressive disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 56, p. 101.
Whalley, H. C. Sussmann, J. E. Romaniuk, L. Stewart, T. Kielty, S. Lawrie, S. M. Hall, J. and McIntosh, A. M. 2015. Dysfunction of emotional brain systems in individuals at high risk of mood disorder with depression and predictive features prior to illness. Psychological Medicine, Vol. 45, Issue. 06, p. 1207.
Brooks, John O. and Vizueta, Nathalie 2014. Diagnostic and clinical implications of functional neuroimaging in bipolar disorder. Journal of Psychiatric Research, Vol. 57, p. 12.
Delle-Vigne, D. Wang, W. Kornreich, C. Verbanck, P. and Campanella, S. 2014. Emotional facial expression processing in depression: Data from behavioral and event-related potential studies. Neurophysiologie Clinique/Clinical Neurophysiology, Vol. 44, Issue. 2, p. 169.
Depression in the context of bipolar disorder (BDd) is often misdiagnosed as unipolar disorder depression (UDd) leading to poor clinical outcomes for many bipolar sufferers. We examined neural circuitry supporting emotion regulation in females with either BDd or UDd as a first stage toward identifying biomarkers that may differentiate BDd from UDd.
Fifty-seven females aged 18–45 years participated in this study: 23 with UDd, 18 with bipolar disorder type I depression (BDId) and 16 healthy females. During 3-T functional magnetic resonance imaging (fMRI), the participants performed an emotional face n-back (EFNBACK) task, that is an n-back task with high (2-back) and low (0-back) memory load conditions flanked by two positive, negative or neutral face distracters. This paradigm examines executive control with emotional distracters–emotion regulation.
High memory load with neutral face distracters elicited greater bilateral and left dorsal anterior midcingulate cortex (dAMCC) activity in UDd than in healthy and BDId females respectively, and greater bilateral putamen activity in both depressed groups versus healthy females. High memory load with happy face distracters elicited greater left putamen activity in UDd than in healthy females. Psychotropic medication was associated with greater putamen activity to these contrasts in UDd females.
During high memory load with neutral face distracters, elevated dAMCC activity in UDd suggests abnormal recruitment of attentional control circuitry to maintain task performance, whereas elevated putamen activity unrelated to psychotropic medication in BDId females may suggest an attentional bias toward ambiguous neutral face distracters. Differential patterns of functional abnormalities in neural circuitry supporting attentional control during emotion regulation, especially in the dAMCC, is a promising neuroimaging measure to distinguish UDd from BDId in females.
This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.
Email your librarian or administrator to recommend adding this journal to your organisation's collection.