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Food antibodies in acute psychoses

  • K. J. B. Rix (a1), Janet Ditchfield (a1), D. L. J. Freed (a1), D. P. Goldberg (a1) and Valerie F. Hillier (a1)...
Abstract
Synopsis

Antibodies to a variety of foods, and in particular cereals, were measured in serum from 100 patients with acute psychoses and 100 elective surgical patients. For 13 out of 14 foods to which non-IgE antibodies were detected the schizophrenics had slightly more antibodies than the controls. There was an association between a possible secondary mania and the presence of IgE antibodies to wheat or rye. However, neither the schizophrenia nor the mania findings can be regarded as evidence for food allergy causing psychiatric disorder, since the immunological findings in both cases may represent consequences of the illnesses or their treatment, rather than causes of the illness.

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Corresponding author
1Address for correspondence: Dr K. J. B. Rix, University Department of Psychiatry, St James's University Hospital, Leeds LS9 7TF.
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F. C. Dohan (1966 a). Wartime changes in hospital admissions for schizophrenia. Acta Psychiatrica Scandinavica 42, 123.

F. C. Dohan (1966 b). Cereals and schizophrenia. Data and hypothesis. Acta Psychiatrica Scandinavica 42, 125152.

K. P. Eterman , W. Th. J. M. Hekkens , A. S. Pena , P. H. Lems-van-Kan & T. E. W. Feltkamp (1977). Wheat grains: a substrate for the determination of gluten antibodies in serum of gluten-sensitive patients. Journal of Immunological Methods 14, 8592.

R. S. Farr (1958). A quantitative immunochemical measure of the primary interactions between I*BSA and antibody. Journal of Infectious Diseases 103, 239262.

W. Th. J. M. Hekkens , A. J. M. Schipperijn & D. L. J. Freed (1980). Antibodies to wheat proteins in schizophrenia: relationship or coincidence? Biochemistry of Schizophrenia and Addiction (ed. G. Hemmings ), pp. 125133. MTP Press: Lancaster.

D. R. Hoffman (1975). The specificities of human IgE antibodies combining with cereal grains. Immunochemistry 12, 535538.

P. J. Huxley , D. P. Goldberg , G. P. Maguire & V. A. Kincey (1979). The prediction of the course of minor psychiatric disorders. British Journal of Psychiatry 135, 535543.

C. D. May , L. Remigio , J. Feldman , S. A. Bock & R. I. Carr (1977). A study of serum antibodies to isolated milk proteins and ovalbumin in infants and children. Clinical Allergy 7, 583595.

T. G. Merrett & J. Merrett (1978). Methods of quantifying circulating IgE. Clinical Allergy 8, 543557.

T. Schweder & E. Spjøtvoll (1982). Plots of P-values to evaluate many tests simultaneously. Biometrika 69, 493502.

D. G. Wraith , J. Merrett , A. Roth , L. Yoman & T. G. Merrett (1979). Recognition of food-allergic patients and their allergens by the RAST technique and clinical investigation. Clinical Allergy 9, 2536.

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Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
  • URL: /core/journals/psychological-medicine
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