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Plasma concentrations of tryptophan and other amino acids in manic-depressive patients1

Published online by Cambridge University Press:  09 July 2009

Jancis R. Rees
Affiliation:
Department of Biochemistry, University of Leeds
M. N. E. Allsopp
Affiliation:
Department of Biochemistry, University of Leeds
R. P. Hullin*
Affiliation:
Department of Biochemistry, University of Leeds
*
2Address for correspondence: Dr. R. P. Hullin, Department of Biochemistry, 9 Hyde Terrace, Leeds LS2 9LS.

Sysnopsis

Plasma tryptophan concentrations were determined in serial blood samples from a short cycle (two to three day) manic-depressive patient and four manic-depressive patients with longer (60 day) affective cycles. Tryptophan levels varied significantly with affective state in the short cycle patient and one of the longer cycle patients. Correlation in the short cycle patient was better with blood samples taken at 3 p.m. than at 9 a.m.

Type
Preliminary communication
Copyright
Copyright © Cambridge University Press 1974

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Footnotes

1

The work was supported by an M.R.C. long-term programme grant to R. P. Hullin.

References

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