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Preliminary Communication Thyro-endocrine pathology, obstetric morbidity and schizophrenia: survey of a hundred families with a schizophrenic proband

  • David MacSweeney (a1), Pauline Timms (a1) and Anthony Johnson (a1)

This preliminary communication reports that the mothers of 104 schizophrenic patients had: (1) a significantly higher incidence of thyroid disease than a carefully matched control group; (2) significantly more abortions, still-births and greater infant mortality. The findings and possible relevance of thyroid disease to schizophrenia are discussed. Three prospective studies currently in progress are outlined.

Corresponding author
1Address for correspondence: Dr David MacSweeney, Academic Department of Psychiatry, Middlesex Hospital Medical School, London W1P 8AA.
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Psychological Medicine
  • ISSN: 0033-2917
  • EISSN: 1469-8978
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