Hostname: page-component-76fb5796d-9pm4c Total loading time: 0 Render date: 2024-04-25T18:23:50.930Z Has data issue: false hasContentIssue false

Sickness absence: a systematic review and meta-analysis of psychological treatments for individuals on sick leave due to common mental disorders

Published online by Cambridge University Press:  30 January 2018

Sigrid Salomonsson*
Affiliation:
Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
Erik Hedman-Lagerlöf
Affiliation:
Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
Lars-Göran Öst
Affiliation:
Department of Psychology, Stockholm University, Stockholm, Sweden
*
Author for correspondence: Sigrid Salomonsson, E-mail: sigrid.salomonsson@sll.se

Abstract

Sick leave due to common mental disorders (CMDs) increase rapidly and present a major societal challenge. The overall effect of psychological interventions to reduce sick leave and symptoms has not been sufficiently investigated and there is a need for a systematic review and meta-analysis of the field. The aim of the present meta-analysis was to calculate the effect size of psychological interventions for CMDs on sick leave and psychiatric symptoms based on all published randomized controlled trials. Methodological quality, the risk of bias and publication bias were also assessed. The literature searches gave 2240 hits and 45 studies were included. The psychological interventions were more effective than care as usual on both reduced sick leave (g = 0.15) and symptoms (g = 0.21). There was no significant difference in effect between work focused interventions, problem-solving therapy, cognitive behavioural therapy or collaborative care. We conclude that psychological interventions are more effective than care as usual to reduce sick leave and symptoms but the effect sizes are small. More research is needed on psychological interventions that evaluate effects on sick leave. Consensual measures of sick leave should be established and quality of psychotherapy for patients on sick leave should be improved.

Type
Review Article
Copyright
Copyright © Cambridge University Press 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Arends, I, Bruinvels, DJ, Rebergen, DS, Nieuwenhuijsen, K, Madan, I, Neumeyer-Gromen, A et al. (2012) Interventions to facilitate return to work in adults with adjustment disorders. Cochrane Database Systemic Reviews 12, Art. No.: CD006389.Google Scholar
Bakker, IM, Van Marwijk, HW, Terluin, B, Anema, JR, Van Mechelen, W and Stalman, WA (2010) Training GP's to use a minimal intervention for stress-related mental disorders with sick leave (MISS): effects on performance: results of the MISS project; a cluster-randomised controlled trial [ISRCTN43779641]. Patient Education and Counseling 78, 206211.Google Scholar
Blonk, RW, Brenninkmeijer, V, Lagerveld, SE and Houtman, IL (2006) Return to work: a comparison of two cognitive behavioural interventions in cases of work-related psychological complaints among the self-employed. Work and Stress 20, 129144.Google Scholar
Brouwers, EP, Tiemens, BG, Terluin, B and Verhaak, PF (2006) Effectiveness of an intervention to reduce sickness absence in patients with emotional distress or minor mental disorders: a randomized controlled effectiveness trial. General Hospital Psychiatry 28, 223229.Google Scholar
Carta, MG, Balestrieri, M, Murru, A and Hardoy, MC (2009) Adjustment disorder: epidemiology, diagnosis and treatment. Clinical Practice and Epidemiology in Mental Health 5, 1745–0179.Google Scholar
Comer, JS, Blanco, C, Hasin, DS, Liu, SM, Grant, BF, Turner, JB et al. (2011) Health-related quality of life across the anxiety disorders: results from the national epidemiologic survey on alcohol and related conditions (NESARC). Journal of Clinical Psychiatry 72, 4350.Google Scholar
Cuijpers, P, Berking, M, Andersson, G, Quigley, L, Kleiboer, A and Dobson, KS (2013) A meta-analysis of cognitive-behavioural therapy for adult depression, alone and in comparison with other treatments. Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie 58, 376385.Google Scholar
Cuijpers, P, Sijbrandij, M, Koole, S, Huibers, M, Berking, M and Andersson, G (2014) Psychological treatment of generalized anxiety disorder: a meta-analysis. Clinical Psychology Review 34, 130140.Google Scholar
Cusack, K, Jonas, DE, Forneris, CA, Wines, C, Sonis, J, Middleton, JC et al. (2016) Psychological treatments for adults with posttraumatic stress disorder: a systematic review and meta-analysis. Clinical Psychology Review 43, 128141.Google Scholar
De Vente, W, Kamphuis, JH, Emmelkamp, PM and Blonk, RW (2008) Individual and group cognitive-behavioral treatment for work-related stress complaints and sickness absence: a randomized controlled trial. Journal of Occupational Health Psychology 13, 214231.Google Scholar
Doki, S, Sasahara, S and Matsuzaki, I (2015) Psychological approach of occupational health service to sick leave due to mental problems: a systematic review and meta-analysis. International Archives of Occupational and Environmental Health 88, 659667.Google Scholar
Duval, S and Tweedie, R (2000) Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56, 455463.Google Scholar
Ebert, DD, Heber, E, Berking, M, Riper, H and Cuijpers, P (2016) Self-guided internet-based and mobile-based stress management for employees: results of a randomised controlled trial. Occupational and Environmental Medicine 73, 315323.Google Scholar
Ebert, DD, Lehr, D, Boss, L, Riper, H, Cuijpers, P, Andersson, G et al. (2014) Efficacy of an internet-based problem-solving training for teachers: results of a randomized controlled trial. Scandinavian Journal of Work, Environment and Health 40, 582596.Google Scholar
Egger, M, Davey Smith, G, Schneider, M and Minder, C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315, 629634.Google Scholar
Ejeby, K, Savitskij, R, Ost, L-G, Ekbom, A, Brandt, L, Ramnero, J et al. (2014) Symptom reduction due to psychosocial interventions is not accompanied by a reduction in sick leave: results from a randomized controlled trial in primary care. Scandinavian Journal of Primary Health Care 32, 6772.Google Scholar
Eriksson, UB, Starrin, B and Janson, S (2008) Long-term sickness absence due to burnout: absentees’ experiences. Qualitative Health Research 18, 620632.Google Scholar
Fernandez, A, Mendive, JM, Salvador-Carulla, L, Rubio-Valera, M, Luciano, JV, Pinto-Meza, A et al. (2012) Adjustment disorders in primary care: prevalence, recognition and use of services. British Journal of Psychiatry 201, 137142.Google Scholar
Hägglund, P, Johansson, P and Laun, L (2014) ISF Report: The Effects of the Swedish Rehabilitation Guarantee on Health and Sickness Absence. Stockholm: Swedish Social Insurance Inspectorate.Google Scholar
Henderson, M, Glozier, N and Holland Elliott, K (2005) Long term sickness absence. BMJ 9, 802803.Google Scholar
Henderson, M, Harvey, SB, Overland, S, Mykletun, A and Hotopf, M (2011) Work and common psychiatric disorders. Journal of the Royal Society of Medicine 104, 198207.Google Scholar
Higgins, JP, Altman, DG, Gotzsche, PC, Juni, P, Moher, D, Oxman, AD et al. (2011) The cochrane collaboration's tool for assessing risk of bias in randomised trials. BMJ 343, d5928.Google Scholar
Jadad, AR, Moore, RA, Carroll, D, Jenkinson, C, Reynolds, DJ, Gavaghan, DJ et al. (1996) Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled Clinical Trials 17, 112.Google Scholar
Kessler, RC, Berglund, P, Demler, O, Jin, R, Merikangas, KR and Walters, EE (2005) Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication. Archives of General Psychiatry 62, 593602.Google Scholar
Koopmans, PC, Bultmann, U, Roelen, CA, Hoedeman, R, Van Der Klink, JJ and Groothoff, JW (2011) Recurrence of sickness absence due to common mental disorders. International Archives of Occupational and Environmental Health 84, 193201.Google Scholar
Mayo-Wilson, E, Dias, S, Mavranezouli, I, Kew, K, Clark, DM, Ades, AE et al. (2014) Psychological and pharmacological interventions for social anxiety disorder in adults: a systematic review and network meta-analysis. Lancet Psychiatry 1, 368376.Google Scholar
National Institute for Health and Clinical Excellence [NICE] (2011 a) Common Mental Health Disorders: Identification and Pathways to Care – Clinical Guideline [Online]. Leicester, UK: National Institute for Health and Clinical Excellence. Available at https://www.nice.org.uk/guidance/cg123 (Accessed 27 June 2017).Google Scholar
NICE (2011 b) Generalised Anxiety Disorder and Panic Disorder in Adults: Management – Clinical Guideline [Online]. Available at www.nice.org.uk/guidance/cg113 (Accessed 27 June 2017).Google Scholar
Nielsen, MB, Bultmann, U, Madsen, IE, Martin, M, Christensen, U, Diderichsen, F et al. (2012). Health, work, and personal-related predictors of time to return to work among employees with mental health problems. Disability and Rehabilitation 34, 13111316.Google Scholar
Nieuwenhuijsen, K, Faber, B, Verbeek, JH, Neumeyer-Gromen, A, Hees, HL, Verhoeven, AC et al. (2014) Interventions to improve return to work in depressed people. Cochrane Database of Systematic Reviews 3, Art. No.: CD006237.Google Scholar
Nigatu, YT, Liu, Y, Uppal, M, Mckinney, S, Rao, S, Gillis, K et al. (2016) Interventions for enhancing return to work in individuals with a common mental illness: systematic review and meta-analysis of randomized controlled trials. Psychological Medicine 46, 32633274.Google Scholar
OECD (2012) Sick on the Job? Paris: OECD Publishing.Google Scholar
Ohayon, MM (2002) Epidemiology of insomnia: what we know and what we still need to learn. Sleep Medicine Reviews 6, 97111.Google Scholar
Öst, LG (2008) Efficacy of the third wave of behavioral therapies: a systematic review and meta-analysis. Behaviour Research and Therapy 46, 296321.Google Scholar
Öst, LG (2014) The efficacy of acceptance and commitment therapy: an updated systematic review and meta-analysis. Behaviour Research and Therapy 61, 105121.Google Scholar
Öst, L-G (2016) Att Utvärdera Psykoterapi och Kritiskt Granska Psykoterapistudier [In English: To Evaluate Psychotherapy and Critically Review Psychotherapy Studies]. Stockholm: Natur & Kultur.Google Scholar
Öst, LG, Havnen, A, Hansen, B and Kvale, G (2015) Cognitive behavioral treatments of obsessive-compulsive disorder. A systematic review and meta-analysis of studies published 1993–2014. Clinical Psychology Review 40, 156169.Google Scholar
Öst, LG and Ollendick, TH (2017) Brief, intensive and concentrated cognitive behavioral treatments for anxiety disorders in children: a systematic review and meta-analysis. Behaviour Research and Therapy 97, 134145.Google Scholar
Öst, LG, Riise, EN, Wergeland, GJ, Hansen, B and Kvale, G (2016) Cognitive behavioral and pharmacological treatments of OCD in children: a systematic review and meta-analysis. Journal of Anxiety Disorders 43, 5869.Google Scholar
Rost, K, Smith, JL and Dickinson, M (2004) The effect of improving primary care depression management on employee absenteeism and productivity. A randomized trial. Medical Care 42, 12021210.Google Scholar
Sanchez-Meca, J, Rosa-Alcazar, AI, Marin-Martinez, F and Gomez-Conesa, A (2010) Psychological treatment of panic disorder with or without agoraphobia: a meta-analysis. Clinical Psychology Review 30, 3750.Google Scholar
Schoenbaum, M, Unutzer, J, Sherbourne, C, Duan, N, Rubenstein, LV, Miranda, J et al. (2001) Cost-effectiveness of practice-initiated quality improvement for depression: results of a randomized controlled trial. JAMA 286, 13251330.Google Scholar
Simon, GE, Katon, W, Rutter, C, Vonkorff, M, Lin, E, Robinson, P et al. (1998) Impact of improved depression treatment in primary care on daily functioning and disability. Psychological Medicine 28, 693701.Google Scholar
Taimela, S, Aronen, P, Malmivaara, A, Sintonen, H, Tiekso, J and Aro, T (2010) Effectiveness of a targeted occupational health intervention in workers with high risk of sickness absence: baseline characteristics and adherence as effect modifying factors in a randomized controlled trial. Journal of Occupational Rehabilitation 20, 1420.Google Scholar
The Swedish Social Insurance Agency (2014) Social Insurance Report 2014:4. Stockholm: DanagårdLiTHO.Google Scholar
Van Der Klink, JJ, Blonk, RW, Schene, AH and Van Dijk, FJ (2003) Reducing long term sickness absence by an activating intervention in adjustment disorders: a cluster randomised controlled design. Occupational and Environmental Medicine 60, 429437.Google Scholar
Van Oostrom, SH, Van Mechelen, W, Terluin, B, De Vet, HC, Knol, DL and Anema, JR (2010) A workplace intervention for sick-listed employees with distress: results of a randomised controlled trial. Occupational and Environmental Medicine 67, 596602.Google Scholar
Van Vilsteren, M, Van Oostrom, SH, De Vet, HC, Franche, RL, Boot, CR and Anema, JR (2015) Workplace interventions to prevent work disability in workers on sick leave. Cochrane Database of Systematic Reviews (10), Cd006955.Google Scholar
Wang, PS, Simon, GE, Avorn, J, Azocar, F, Ludman, EJ, Mcculloch, J et al. (2007) Telephone screening, outreach, and care management for depressed workers and impact on clinical and work productivity outcomes: a randomized controlled trial. JAMA 298, 14011411.Google Scholar
Wells, KB, Stewart, A, Hays, RD, Burnam, MA, Rogers, W, Daniels, M et al. (1989) The functioning and well-being of depressed patients. Results from the Medical Outcomes study. JAMA 262, 914919.Google Scholar
Willert, MV, Thulstrup, AM and Bonde, JP (2011) Effects of a stress management intervention on absenteeism and return to work – results from a randomized wait-list controlled trial. Scandinavian Journal of Work, Environment and Health 37, 186195.Google Scholar
Vlasveld, MC, Van Der Feltz-Cornelis, CM, Ader, HJ, Anema, JR, Hoedeman, R, Van Mechelen, W et al. (2013) Collaborative care for sick-listed workers with major depressive disorder: a randomised controlled trial from the Netherlands depression initiative aimed at return to work and depressive symptoms. Occupational and Environmental Medicine 70, 223230.Google Scholar
Volker, D, Zijlstra-Vlasveld, MC, Anema, JR, Beekman, AT, Brouwers, EP, Emons, WH et al. (2015) Effectiveness of a blended web-based intervention on return to work for sick-listed employees with common mental disorders: results of a cluster randomized controlled trial. Journal of Medical Internet Research 17, e116.Google Scholar
Supplementary material: File

Salomonsson et al. supplementary material

Salomonsson et al. supplementary material 1

Download Salomonsson et al. supplementary material(File)
File 250.8 KB