Hostname: page-component-76fb5796d-25wd4 Total loading time: 0 Render date: 2024-04-28T07:24:01.266Z Has data issue: false hasContentIssue false

A review of cognitive and neurolinguistic deficits in Parkinson's disease

Published online by Cambridge University Press:  05 May 2015

Paul A. Watters
Affiliation:
, Department of Computing, Macquarie University NSW 2109, AUSTRALIA
Jennifer M. Gurd
Affiliation:
, Neuropsychology Unit, University Department of Clinical Neurology, The Radcliffe Infirmary NHS Trust, Woodstock Road, Oxford OX2 6HE, U.K.

Abstract

Parkinson's Disease (PD) is a neurological disorder which appears to be increasing in prevalence in the Asia-Pacific region among the elderly. Although PD is considered by many as a motor syndrome, its physiological basis in dopaminergic pathways has recently been associated with cognitive and neurolinguistic changes. This paper attempts to synthesise the common threads running through clinical and empirical work which has supported a specific cognitive word-finding deficit in PD. Recent computational accounts of the observed deficits are also reviewed as one way of testing theories of PD-like lexical-semantic errors, and generating empirically-testable hypotheses.

Type
Part IV. Language and Ageing
Copyright
Copyright © University of Papua New Guinea and the Centre for Southeast Asian Studies, Northern Territory University, Australia 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Alexander, M.P. and Crutcher, M.D. (1990) Functional architecture of basal ganglia circuits: Neural substrates of parallel processing. Trends in Neuroscience, 13, 266271.CrossRefGoogle ScholarPubMed
Auriacombe, S., Grossman, M., Carvell, S., Gollomp, S., Stern, M., & Hurtig, H. (1993). Verbal fluency deficits in Parkinson's Disease. Neuropsychology, 7, 182192.CrossRefGoogle Scholar
Bailey-Wilson, J., Plato, C., Elston, R., & Garruto, R. (1993). Potential role of an additive genetic component in the cause of amyotrophic lateral sclerosis and parkinsonism-dementia in the western Pacific. American Journal of Medical Genetics, 45, 6876.CrossRefGoogle ScholarPubMed
Beatty, W., & Monson, N. (1989). Lexical processing in Parkinson's disease and multiple sclerosis. Journal of Geriatric Psychiatry and Neurology, 2, 145152.CrossRefGoogle ScholarPubMed
Braak, H., Braak, E., Yilmazer, D., de Vos, R., Jansen, E., & Bohl, J. (1996). Pattern of brain destruction in Parkinson's and Alzheimer's diseases. Journal of Neural Transmission, 103, 455490.CrossRefGoogle ScholarPubMed
Brod, M., Mendelsohn, G.A., Roberts, B. (1998). Patients' experiences of Parkinson's disease. Journals Of Gerontology: Series B, Psychological Sciences And Social Sciences, 53, P213P222.CrossRefGoogle ScholarPubMed
Chapman, L. & Chapman, J. (1964). The interpretation of words in schizophrenia. Journal of Abnormal Social Psychology, 65.Google Scholar
Chapman, L., Chapman, J., & Miller, G. (1964). A theory of verbal behavior in schizophrenia. Progress in Experimental Personality Research, 1, 4977.Google Scholar
Cohen, H. (1998). Language impairment in Parkinson's disease. In Stemmer, B. & Whitaker, H. (Eds.), Handbook of Neurolinguistics. San Diego: Academic Press.Google Scholar
Collins, A.M., & Quillan, M.R. (1969). Retrieval time from semantic memory. Journal of Verbal Learning and Verbal Behaviour, 8, 240247.CrossRefGoogle Scholar
Coltheart, M., Curtis, B., Atkins, P., & Haller, M. (1993). Models of reading aloud: dual-route and parallel-distributed-processing approaches. Psychological Review, 100, 589608.CrossRefGoogle Scholar
Critchley, E. (1981). Speech disorders of Parkinsonism: A review. Journal of Neurology, Neurosurgery & Psychiatry, 44, 751758.CrossRefGoogle ScholarPubMed
Doyon, J., Bourgeois, C., & Bedard, P., (1996). Visuo-spatial deficits associated with Parkinson's disease. International Journal of Psychology, 31, 161175.CrossRefGoogle Scholar
Dromey, C., Ramig, L., & Johnson, A. (1995). Phonatory and articulatory changes associated with increased vocal intensity in Parkinson disease: A case study. Journal of Speech and Hearing Research, 38, 751764.CrossRefGoogle ScholarPubMed
Gerlach, M., Gsell, W., Kornhuber, J., Jellinger, K., Krieger, V., Pantucek, F., Vock, R., & Riederer, P. (1996). A post mortem study on neurochemical markers of dopaminergic, GABA-ergic and glutamatergic neurons in basal ganglia-thalamocortical circuits in Parkinson syndrome. Brain Research, 741, 142152.CrossRefGoogle Scholar
Geyer, H.L., & Grossman, M. (1994). Investigating the basis for the sentence comprehension deficit in Parkinson's Disease. Journal of Neurolinguistics, 8, 191205.CrossRefGoogle Scholar
Goldman, W., Baty, J., Buckles, V., Sahrmann, S., & Morris, J. (1998). Cognitive and motor functioning in Parkinson disease: Subjects with and without questionable dementia. Archives of Neurology, 55, 674680.CrossRefGoogle ScholarPubMed
Goldman-Rakic, P. S. and Selemon, L.D. (1990) New frontiers in basal ganglia research. Trends in Neuroscience, 13, 241244.CrossRefGoogle ScholarPubMed
Gurd, J.M. (1995). Frontal dissociations: Evidence from Parkinson's disease. Journal of Neurolinguistics, 9, 5568.CrossRefGoogle Scholar
Gurd, J.M. (1996). Word search in patients with Parkinson's disease. Journal of Neurolinguistics, 9, 207218.CrossRefGoogle Scholar
Gurd, J.M., Bessell, N., Watson, I., & Coleman, J. (1997). Motor speech versus digit control in Parkinson's disease: A cognitive neuropsychology investigation. Clinical Linguistics and Phonetics.Google Scholar
Gurd, J.M., & Oliveira, R.M. (1996). Competitive inhibition models of lexical-semantic processing: Experimental evidence. Brain and Language, 54, 414433.CrossRefGoogle ScholarPubMed
Gurd, J.M., & Ward, C.D. (1989). Retrieval from semantic and letter-initial categories in patients with Parkinson's Disease. Neuropsychologia, 27, 743746.CrossRefGoogle ScholarPubMed
Hanley, J., Dewick, H., Davies, A., Playfer, J., & Turnbull, C. (1990). Verbal fluency in Parkinson's disease. Neuropsychologia, 28, 373741.Google ScholarPubMed
Hines, T.M., & Volpe, B.T. (1985). Semantic activation in patients with Parkinson's Disease. Experimental Aging Research, 11, 105107.CrossRefGoogle ScholarPubMed
Hornykiewicz, O. (1998). Biochemical aspects of Parkinson's disease. Neurology, 51, S2S9.CrossRefGoogle ScholarPubMed
Hsieh, S., Hwang, W., Tsai, J., & Tsai, C. (1996). Visuospatial orienting of attention in Parkinson's disease. Perceptual and Motor Skills, 82, 13071315.CrossRefGoogle ScholarPubMed
Imaizumi, Y., & Kaneko, R. (1995). Rising mortality from Parkinson's disease in Japan, 1950-1992. Acta Neurologica Scandinavica, 91, 169176.CrossRefGoogle Scholar
Javoy-Agid, F., & Agid, Y. (1980). Is the mesocortical dopaminergic system involved in Parkinson's disease? Neurology, 30, 13261330.CrossRefGoogle Scholar
Joosten, J., Coenders, C., & Eling, P. (1995). Shifting behavior: An analysis of response patterns of Parkinson patients in discrimination learning. Brain and Cognition, 29, 115126.CrossRefGoogle ScholarPubMed
Kritikos, A., Leahy, C., Bradshaw, J., & Iansek, R. (1995). Contingent and non-contingent auditory cueing in Parkinson's disease. Neuropsychologia, 33, 11931203.CrossRefGoogle ScholarPubMed
Lebrun, Y. (1996). Cluttering after Brain Damage. Journal of Fluency Disorders, 21, 289295.CrossRefGoogle Scholar
Mahieux, F., Michelet, D., Manifacier, M., & Boller, F. (1995). Mini-mental Parkinson: First validation study of a new bedside test constructed for Parkinson's disease. Behavioural Neurology, 8, 1522.CrossRefGoogle ScholarPubMed
Mahurin, R., & Pirozzolo, F. (1993). Application of Hick's law of response speed in Alzheimer and Parkinson diseases. Perceptual and Motor Skills, 77, 107113.CrossRefGoogle ScholarPubMed
McDonald, C., Brown, G., & Gorell, J. (1996). Impaired set-shifting in Parkinson's disease: New evidence from a lexical decision task. Journal of Clinical and Experimental Neuropsychology, 18, 793809.CrossRefGoogle ScholarPubMed
Miller, G.A., Beckwith, R., Fellbaum, C., Gross, D., & Miller, K.J. (1990). Introduction to WordNet: An on-line lexical database. International Journal of Lexicography, 3, 235244.CrossRefGoogle Scholar
Miyata, Y., Tachibana, H., & Sugita, M. (1998). Memory function in aging and Parkinson's disease-an event-related potential study. Nippon Ronen Igakkai Zasshi, 35, 464471.CrossRefGoogle ScholarPubMed
Nakashima, K., Yokoyama, Y., Shimoyama, R., Saito, H., Kuno, N., Sano, K., Rin, Y., Adachi, Y., Urakami, K., Oshima, T., Takeshita, K., & Takahashi, K. (1996). Prevalence of neurological disorders in a Japanese town. Neuroepidemiology, 15, 208213.CrossRefGoogle Scholar
Patel, M. (1996). Using neural nets to investigate lexical analysis. In: Foo, N & Goebel, R. (Eds.). Lecture Notes in Artifical Intelligence 1114. Berlin: Springer.Google Scholar
Patel, M. & Watters, P.A. (1998). Semantic judgement errors in Parkinson's Disease: The role of priming. Proceedings of the 5th Neural Computation and Psychology Workshop, University of Birmingham, UK.Google Scholar
Pomati, S., Farina, E., Magni, E., & Laiacona, M. (1996). Normative data for two neuropsychological tests sensitive to frontal dysfunction. Italian Journal of Neurological Sciences, 17, 201209.CrossRefGoogle ScholarPubMed
Ramig, L., Countryman, S., Thompson, L., & Horii, Y. (1995). Comparison of two forms of intensive speech treatment for Parkinson disease. Journal of Speech and Hearing Research, 38, 12321251.CrossRefGoogle ScholarPubMed
Raskin, S., Sliwinksi, M., & Borod, J. (1992). Clustering strategies on tasks of verbal fluency in Parkinson's disease. Neuropsychologia, 30, 9599.CrossRefGoogle ScholarPubMed
Ringendahl, H. (1996). Memory disturbances in Parkinson's disease. Fortschritte der Neurologie - Psychiatrie, 64, 4348.CrossRefGoogle ScholarPubMed
Robbins, T. (1981). Cognitive deficits in schizophrenia and Parkinson's Disease: Neural basis and the role of dopamine. In Willner, P. & Scheel-Kurger, J. (Eds.). The Mesolimbic Dopamine System: From Motivation to Action. Chichester: Wiley.Google Scholar
Salmon, D.P., Galasko, D., Hansen, L.A., Masliah, E., Butters, N., Thai, L.J. and Katzman, R. (1996) Neuropsychological deficits associated with diffuse Lewy body disease. Brain & Cognition, 31, 148–65.CrossRefGoogle ScholarPubMed
Schwab, S. & Vilsmeier, M. (1998). Planning abilities and planning deficiencies of patients with Parkinson's disase: Diagnostics by means of tutorial day planning task. Zeitschrift fuer Neuropsychologie, 9, 1829.Google Scholar
Sitaramayya, A., Lombardi, L., & Margulis, A. (1993). Influence of dopamine on cyclic nucleotide enzymes in bovine retinal membrane fractions. Visual Neuroscience, 10, 991996.CrossRefGoogle ScholarPubMed
Soukup, V., Ingram, F., Schiess, M., Bonnen, J., Nauta, H., & Calverley, J., (1997). Cognitive sequelae of unilateral posteroventral pallidotomy. Archives of Neurology, 54, 947950.CrossRefGoogle ScholarPubMed
Spicer, K., Brown, G., & Gorell, J., (1994). Lexical decision in Parkinson disease: Lack of evidence for generalized bradyphrenia. Journal of Clinical and Experimental Neuropsychology, 16, 457471.CrossRefGoogle ScholarPubMed
Stemberger, J.P. (1985). An interactive activation model of language production. In Ellis, A. (Ed.). Progress in the Psychology of Language. London: Erlbaum.Google Scholar
Tomer, R., Levin, B.E., & Weiner, W.J. (1993). Side of onset of motor symtpoms influences cognition in Parkinson's disease. Annals of Neurology, 34, 579584.CrossRefGoogle Scholar
Tweedy, J.R., Langer, K.G., & McDowell, F.H. (1982). The effect of semantic relations On the memory deficit associated with Parkinson's disease. Journal of Clinical Neuropsychology, 4, 235247.CrossRefGoogle ScholarPubMed
Twilley, L.C., Dixon, D., Taylor, D., & Clark, K. (1994). University of norms of relative meaning frequency for 566 homographs. Memory and Cognition, 22, 111126.CrossRefGoogle ScholarPubMed
Van Spaendonck, K.P., Berger, H.J., Horstink, M.W., Borm, G.F., & Cools, A.R. (1996). Memory performance under varying cueing conditions in patients with Parkinson's disease. Neuropsychologia, 34, 11591164.CrossRefGoogle ScholarPubMed
Wang, S.J., Fuh, J.L., Teng, E.L., Liu, C.Y., Lin, K.P., Chen, H.M., Lin, C.H., Wang, P.N., Ting, Y.C., Wang, H.C., Lin, K.N., Chou, P., Larson, E.B., & Liu, H.C. (1997). A door-to-door survey of Parkinson's disease in a Chinese population in Kinmen. Archives of Neurology, 53, 6671.CrossRefGoogle Scholar
Watters, P.A. (1998). Cognitive theory and neural model: The role of local representation [Commentary on Green on Connectionist-Explanation]. Psycoloquy, 9: 20.Google Scholar
Watters, P.A. & Patel, M. (1999). Semantic processing deficits in Parkinson's Disease: Degraded representation or defective retrieval? Journal of Psychiatry and Neuroscience.Google ScholarPubMed
Watters, P.A. & Patel, M. (1998). A neural network model of semantic processing errors in Parkinson's Disease. Neural Processing Letters, 9, 111.Google Scholar
Wilkins, A. (1971). Conjoint frequency, category size, and categorisation time. Journal of Verbal Learning and Verbal Behaviour, 10, 382385.CrossRefGoogle Scholar
Woo, J., Ho, S.C., Lau, S., Lau, J., & Yuen, Y.K. (1994). Prevalence of cognitive impairment and associated factors among elderly Hong Kong Chinese aged 70 years and over. Neuroepidemiology, 13, 5058.CrossRefGoogle ScholarPubMed