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Cousin Marriages and Schizophrenia in Saudi Arabia

Published online by Cambridge University Press:  02 January 2018

Kutaiba Chaleby*
Affiliation:
Department of Medicine, King Faisal Specialist Hospital and Research Centre, PO Box 3354, Riyadh 11211, Saudi Arabia
T. A. Tuma
Affiliation:
Riyadh Psychiatric Hospital, Riyadh 11196, Saudi Arabia
*
Correspondece

Abstract

The rate and degree of consanguinity in the parents of 143 schizophrenics who satisfied the DSM-III diagnostic criteria, was compared in the same number of controls matched for age, sex and socioeconomic class. A family history of disorders suggestive of schizophrenia in the offspring of consanguineous parents who were schizophrenic, was compared with the incidence of a similar history in the schizophrenic offspring of non-consanguineous parents. There was no statistically significant difference in the former, but there was in the latter. This finding supports the theory of a familial tendency towards schizophrenia and the possibility of recessive or a multigene pattern of inheritance.

Type
Brief Reports
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

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