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Cousin Marriages and Schizophrenia in Saudi Arabia

Published online by Cambridge University Press:  02 January 2018

Kutaiba Chaleby*
Department of Medicine, King Faisal Specialist Hospital and Research Centre, PO Box 3354, Riyadh 11211, Saudi Arabia
T. A. Tuma
Riyadh Psychiatric Hospital, Riyadh 11196, Saudi Arabia


The rate and degree of consanguinity in the parents of 143 schizophrenics who satisfied the DSM-III diagnostic criteria, was compared in the same number of controls matched for age, sex and socioeconomic class. A family history of disorders suggestive of schizophrenia in the offspring of consanguineous parents who were schizophrenic, was compared with the incidence of a similar history in the schizophrenic offspring of non-consanguineous parents. There was no statistically significant difference in the former, but there was in the latter. This finding supports the theory of a familial tendency towards schizophrenia and the possibility of recessive or a multigene pattern of inheritance.

Brief Reports
Copyright © 1987 The Royal College of Psychiatrists 

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