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A Controlled Assessment of Propranolol in the Treatment of Neuroleptic-Induced Akathisia

Published online by Cambridge University Press:  29 January 2018

Lenard Adler*
Affiliation:
Department of Psychiatry, New York University Medical Center and Psychiatry Service (116A), New York Veteran's Administration Medical Center First Avenue and East 24th Street, New York, NY10010, USA
Burt Angrist
Affiliation:
Department of Psychiatry, New York University Medical Center and Psychiatry Service (116A), New York Veteran's Administration Medical Center First Avenue and East 24th Street, New York, NY10010, USA
Eric Peselow
Affiliation:
Department of Psychiatry, New York University Medical Center and Psychiatry Service (116A), New York Veteran's Administration Medical Center First Avenue and East 24th Street, New York, NY10010, USA
June Corwin
Affiliation:
Department of Psychiatry, New York University Medical Center and Psychiatry Service (116A), New York Veteran's Administration Medical Center First Avenue and East 24th Street, New York, NY10010, USA
Robert Maslansky
Affiliation:
Department of Medicine, New York University Medical Center, 550 First Avenue, New York, NY10016, USA
John Rotrosen
Affiliation:
Department of Psychiatry, New York University Medical Center and Psychiatry Service (116A), New York Veteran's Administration Medical Center First Avenue and East 24th Street, New York, NY10010, USA
*
Correspondence.

Abstract

Twelve patients with neuroleptic-induced akathisia were treated in a randomised, double-blind, cross-over design with propranolol and matching placebo. Propranolol caused significant decrements in both subjective and objective ratings of akathisia, but not in anxiety scores. This confirms prior findings of the efficacy of propranolol in akathisia induced by neuroleptic treatment.

Type
Papers
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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