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Genetic Counselling for Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Adrianne Reveley
Adrianne Reveley*
Affiliation:
The Maudsley Hospital, Denmark Hill, London SE5 8AZ
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Summary

It is possible that genes contributing to the development of schizophrenia may be identified within the next decade. Genetic methods are improving rapidly, and are surrounded by great public interest. Requests for genetic counselling are keeping pace with this increased attention, but the problems faced by psychiatric genetic counsellors are complex, and the experience of offering such counselling and the issues involved are rarely discussed. In this context the paper describes a year's work counselling for schizophrenia in the Maudsley Hospital Genetic Clinic.

Type
Annotation
Information
The British Journal of Psychiatry , Volume 147 , Issue 2 , August 1985 , pp. 107 - 112
Copyright
Copyright © 1985 The Royal College of Psychiatrists 

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References

Baraitser, M. (1982) The Genetics of Neurological Disorders. Oxford Monographs on Medical Genetics. London: Oxford University Press.Google Scholar
Carter, C. O. (1969) Genetics of common disorders. British Medical Bulletin, 25, 52–57.Google Scholar
Davison, K. & Bagley, C. R. (1969) Schizophrenia like psychoses associated with organic disorders of the central nervous system In Current Problems in Neuropsychiatry. Herrington, R. N. (ed) British Journal of Psychiatry, Special Publication Number 4. Ashford, Kent: Headley Brothers.Google Scholar
Edwards, J. H. (1969) Familial predisposition in man. British Medical Bulletin, 25, 58–64.Google Scholar
Erlenmeyer Kimling, L. (1976) Schizophrenia: A bag of dilemmas. Social Biology, 23, 123–134.CrossRefGoogle ScholarPubMed
Fuhrmann, W. & Vogel, F. (1982) Genetic Counseling 3rd Edition. New York: Springer-Verlag.Google Scholar
Falconer, D. S. (1982) Introduction to Quantitative Genetics 2nd Ed. Longman; London.Google Scholar
Gottesman, I. I. & Shields, J. (1967) A polygenic theory of schizophrenia Proceedings of the National Academy of Sciences (U.S.A.), 58, 199–205.Google Scholar
Gottesman, I. I. & Shields, J. (1982) Schizophrenia: the Epigenetic Puzzle Cambridge: Cambridge University Press.Google Scholar
Gusella, J. F., Wexler, N. S., Conneally, P. M., Naylor, S. L., Anderson, M. A., Tanzi, R. E., Watkins, P. C., Ottina, K., Wallace, M. R., Sakaguchi, A. Y., Young, A. B., Shoulson, I., Bonilla, E. & Martin, J. B. (1983) A polymorphic DNA marker genetically linked to Huntington's disease. Nature, 306, 234–238.CrossRefGoogle ScholarPubMed
Holland, A. J., Hall, A., Murray, R., Russell, G. F. M. & Crisp, A. H. (1984) Anorexia nervosa: A study of 34 twin pairs. British Journal of Psychiatry, 145, 414–419.CrossRefGoogle ScholarPubMed
Karlsson, J. L. (1974) Inheritance of Schizophrenia. Acta Psychiatrica Scandinavica, Supplement 247, Copenhagen: Munksgaard.Google Scholar
Kay, D. W. K. (1978) Assessment of familial risks in the functional psychoses and their application in genetic counselling. British Journal of Psychiatry, 133, 385–403.CrossRefGoogle ScholarPubMed
Kessler, S. (ed) (1979) Genetic Counselling: Psychological Dimensions New York: Academic Press.Google Scholar
Lancet Editorial (1983) Molecular neurobiology and psychiatry, ii, 85.Google Scholar
Lathrop, G. M. Lalouel, J. M., Julier, C. & Ott, J. (1984) Strategies for multilocus linkage analysis in humans Proceedings of the National Academy of Sciences (USA), 81, 3443–3446.CrossRefGoogle ScholarPubMed
Morton, L. A., Kidd, K. K., Matthysse, S. W. & Richards, R. L., (1979) Recurrence risks in schizophrenia: Are they model dependent? Behaviour Genetics, 5, 389–406.Google Scholar
Murray, R. M., Reveley, A. M., Reveley, M. A., Shur, E. & Lewis, S. (1984) Genetic and Environmental Influences in Schizophrenia In Genetic Aspects of Human Behaviour, (eds Sakai, T. & Tsuboi, T. Igaku-Shoin), Tokyo.Google Scholar
Ott, J. (1974) Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. American Journal of Human Genetics, 26, 588–597.Google Scholar
Rosenthal, D. (1974) The Concept of Subschizophrenic Disorders In: Genetics, Environment and Psychopathology. (ed. Mednick, S. A. et al), Amsterdam: North Holland.Google Scholar
Slater, E. (1958) The monogenic theory of schizophrenia Acta Genetica (Basel), 8, 50–56.Google ScholarPubMed
Slater, E. Beard, A. W. & Glithero, E. (1963) The Schizophrenia-like psychoses of epilepsy British Journal of Psychiatry, 109, 95–150.Google Scholar
Slater, E. & Cowie, V. (1971) The Genetics of Mental Disorders, London: Oxford University Press.Google Scholar
Targum, S. D. & Schulz, S. C. (1982) Clinical applications of psychiatric genetics. American Journal of Orthopsychiatry, 52, 45–57.Google Scholar
Tsuang, M. T. (1978) Genetic counselling for psychiatric patients and their families. American Journal of Psychiatry, 135, 1465–1475.Google ScholarPubMed
Tyler, A. & Harper, P. S. (1983) Attitudes of subjects at risk and their relatives towards genetic counselling in Huntington's chorea. Journal of Medical Genetics, 20, 179–188.Google Scholar
Vogel, F. & Motulsky, A. G. (1982) Human Genetics: Springer-Verlag.Google Scholar
Wender, P. H., Rosenthal, D., Kety, S. S., Schulsinger, F. & Welner, J. (1974) Cross-fostering study of schizophrenia. Archives of General Psychiatry, 30, 121–128.CrossRefGoogle Scholar
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