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OPUS study: Suicidal behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis: One-year follow-up of a randomised controlled trial

  • M. Nordentoft (a1), P. Jeppesen (a1), M. Abel (a1), P. Kassow (a2), L. Petersen (a3), A. Thorup (a3), G. Krarup (a4), R. Hemmingsen (a3) and P. Jørgensen (a4)...

Abstract

Background

Patients with first-episode psychosis comprise a high-risk group in terms of suicide.

Aims

To identify predictive factors for suicidal behaviour and to examine the effect of integrated treatment on suicidal behaviour and hopelessness.

Method

A total of 341 patients with a first-episode schizophrenia-spectrum disorder were randomised to integrated treatment or treatment as usual.

Results

During the 1-year follow-up period, 11% attempted suicide. This was associated with female gender, hopelessness, hallucinations and suicide attempt reported at baseline, with the two latter variables being the only significant ones in the final multivariate model. The integrated treatment reduced hopelessness.

Conclusions

Hallucinations and suicide attempt before inclusion in the study were the most significant predictors of suicide attempt in the follow-up period.

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Copyright

Corresponding author

Dr Merete Nordentoft, Department of Psychiatry E, Bispebjerg Hospital, Bispebjerg Bakke 23, DK-2400 Copenhagen NV E-mail: Mereke.Nordentoft@dadlnet.dk

Footnotes

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Presented in part at the European First Episode Schizophrenia Network Meeting, Whistler BC, Canada, 27 April 2001.

Declaration of interest The Danish Ministry of Health, Danish Ministry of Social Affairs, Danish Medical Research Council, Copenhagen Hospital Corporation, Aarhus County and University of Copenhagen have jointly funded the OPUS project.

Footnotes

References

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OPUS study: Suicidal behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis: One-year follow-up of a randomised controlled trial

  • M. Nordentoft (a1), P. Jeppesen (a1), M. Abel (a1), P. Kassow (a2), L. Petersen (a3), A. Thorup (a3), G. Krarup (a4), R. Hemmingsen (a3) and P. Jørgensen (a4)...

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OPUS study: Suicidal behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis: One-year follow-up of a randomised controlled trial

  • M. Nordentoft (a1), P. Jeppesen (a1), M. Abel (a1), P. Kassow (a2), L. Petersen (a3), A. Thorup (a3), G. Krarup (a4), R. Hemmingsen (a3) and P. Jørgensen (a4)...
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