Eckenhoff, RG, Johansson, JS, Wei, H, Carnini, A, Kang, B, Wei, W, et al.
Inhaled anesthetic enhancement of amyloid-beta
oligomerization and cytotoxicity.
2004; 101: 703–9.
Mandal, PK, Fodale, V. Isoflurane and desflurane at clinically relevant
concentrations induce amyloid betapeptide oligomerization: an NMR
study. Biochem Biophys Res Commun
2009; 379: 716–20.
Culley, DJ, Baxter, MG, Crosby, CA, Yukhananov, R, Crosby, G. Long-term impairment of acquisition of a spatial
memory task following isoflurane–nitrous oxide anesthesia in
2004; 100: 309–14.
Planel, E, Richter, KEG, Nolan, CE, Finley, JE, Liu, L, Wen, Y, et al.
Anesthesia leads to tau hyperphosphorylation through
inhibition of phosphatase activity by hypothermia.
2007; 27: 3090–7.
Xie, Z, Culley, DJ, Dong, Y, Zhang, G, Zhang, B, Moir, RD, et al.
The common inhalation anesthetic isoflurane induces caspase
activation and increases amyloid beta-protein level in
vivo. Ann Neurol
2008; 64: 618–27.
Wei, H, Xie, Z. Anesthesia, calcium homeostasis and Alzheimer's
disease. Curr Alzheimer Res
2009; 6: 30–5.
Vanderweydea, T, Bednarb, MM, Formanc, SA, Wolozin, B. Iatrogenic risk factors for Alzheimer's disease:
surgery and anesthesia. J Alzheimers Dis
2010; 22 (suppl 3):
Lee, TA, Wolozin, B, Weiss, KB, Bednar, MM. Assessment of the emergence of Alzheimer's disease
following coronary artery bypass graft surgery or percutaneous
transluminal coronary angioplasty. J Alzheimers
2005; 7: 319–24.
Selnes, OA, Royall, RM, Grega, MA, Borowicz, LM, Quaskey, S, McKhann, GM. Cognitive changes 5 years after coronary artery
bypass grafting. Arch Neurol
Knopman, DS, Petersen, RC, Cha, RH, Edland, SD, Rocca, WA. Coronary artery bypass grafting is not a risk factor
for dementia or Alzheimer disease.
2005; 65: 986–90.
Gasparini, M, Vanacore, N, Schiaffini, C, Brusa, L, Panella, M, Talarico, G, et al.
A case–control study on Alzheimer's disease and exposure to
anesthesia. Neurol Sci
2002; 23: 11–4.
Baranov, D, Bickler, PE, Crosby, GJ, Culley, DJ, Eckenhoff, MF, Eckenhoff, RG, et al.
Consensus statement: First International Workshop on
Anesthetics and Alzheimer's disease. Anesth
2009; 108: 1627–30.
World Health Organization. International
Classification of Diseases, Ninth Revision, Clinical Modification
Charlson, ME, Pompei, P, Ales, KL, Mackenzie, CR. A new method of classifying prognostic comorbidity
in longitudinal studies: development and validation.
J Chron Dis
1987; 40: 373–83.
Futterer, CD, Maurer, MH, Schmitt, A, Feldmann, RE, Kuschinsky, W, Waschke, KF. Alterations in rat brain proteins after desflurane
2004; 100: 302–8.
Duthie, A, Chew, D, Soiza, RL. Non-psychiatric comorbidity associated with
Alzheimer's disease. QJM
2011; 104: 913–20.
Driver, JA, Beiser, A, Au, R, Kreger, BE, Splansky, GL, Kurth, T, et al.
Inverse association between cancer and Alzheimer's disease:
results from the Framingham Heart Study.
Zuo, C, Zuo, Z. Spine surgery under general anesthesia may not
increase the risk of Alzheimer's disease. Dement
Geriatr Cogn Disord
2010; 29: 233–9.
Culley, DJ, Baxter, M, Yukhananov, R, Crosby, G. The memory effects of general anesthesia persist for
weeks in young and aged rats. Anesth
2003; 96: 1004–9.
Bohnen, N, Warner, MA, Kokmen, E, Kurland, LT. Early and midlife exposure to anesthesia and age of
onset of Alzheimer's disease. Int J
1994; 77: 181–5.
Lee, IH, Culley, DJ, Baxter, MG, Xie, Z, Tanzi, RE, Crosby, G. Spatial memory is intact in aged rats after propofol
anesthesia. Anesth Analg
2008; 107: 1211–5.
Palotas, A, Reis, HJ, Bogats, G, Babik, B, Racsmany, M, Engvau, L, et al.
Coronary artery bypass surgery provokes Alzheimer's
disease-like changes in the cerebrospinal fluid.
J Alzheimers Dis
2010; 21: 1153–64.
Williams-Russo, P, Sharrock, NE, Mattis, S, Szatrowski, TP, Charlson, ME. Cognitive effects after epidural vs general
anesthesia in older adults. A randomized trial.
Seitz, DP, Shah, PS, Herrmann, N, Beyene, J, Siddiqui, N. Exposure to general anesthesia and risk of
Alzheimer's disease: a systematic review and
meta-analysis. BMC Geriatr
Farag, E, Chelune, GJ, Schubert, A, Mascha, EJ. Is depth of anesthesia, as assessed by the
Bispectral Index, related to postoperative cognitive dysfunction and
2006; 103: 633–40.
Gardner, BK, O'Connor, DW. A review of the cognitive effects of
electroconvulsive therapy in older adults. J
Bohnen, NI, Warner, MA, Kokmen, E, Beard, CM, Kurland, LT. Alzheimer's disease and cumulative exposure to
anesthesia: a case–control study. J Am Geriatr
Abildstrom, H, Rasmussen, LS, Rentowl, P, Hanning, CD, Rasmussen, H, Kristensen, PA, et al.
Cognitive dysfunction 1–2 years after non-cardiac surgery in
the elderly. Acta Anaesthesiol Scand
2000; 44: 1246–51.
Avidan, MS, Searleman, AC, Storandt, M, Barnett, K, Vannucci, A, Saager, L, et al.
Long-term cognitive decline in older subjects was not
attributable to noncardiac surgery or major illness.
2009; 111: 964–70.
Wan, Y, Xu, J, Ma, D, Zeng, Y, Cibelli, M, Maze, M. Postoperative impairment of cognitive function in
rats: a possible role for cytokine-mediated inflammation in the
2007; 106: 436–43.
Tang, JX, Baranov, D, Hammond, M, Shaw, LM, Eckenhoff, MF, Eckenhoff, RG. Human Alzheimer and inflammation biomarkers after
anesthesia and surgery. Anesthesiology
2011; 115: 727–32.
Cibelli, M, Fidalgo, AR, Terrando, N, Ma, D, Monaco, C, Feldmann, M, et al.
Role of interleukin-1beta in postoperative cognitive
dysfunction. Ann Neurol
2010; 68: 360–8.