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Morphological diversity in terminals of W-type retinal ganglion cells at projection sites in cat brain

Published online by Cambridge University Press:  02 June 2009

Boqing Chen ,
Xiao-Jiang Hu  and
Roberta G. Pourcho
Boqing Chen
Affiliation:
Wayne State University, Detroit
Xiao-Jiang Hu
Affiliation:
Wayne State University, Detroit
Roberta G. Pourcho
Affiliation:
Wayne State University, Detroit
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Abstract

The morphological features of retinal terminals in cat brain were examined at sites where projections of W-type ganglion cells predominate. These included the parvicellular C laminae of the dorsal lateral geniculate nucleus, the ventral lateral geniculate nucleus, stratum griseum superficiale of the superior colliculus, and the suprachiasmatic nucleus. Positive identification of retinal terminals was achieved following anterograde transport of intravitreally injected native or wheat germ agglutinin-conjugated horseradish peroxidase. In contrast to the classic features of retinal terminals as defined from sites where X- and Y-type ganglion cells predominate, i.e. round synaptic vesicles, large profiles, and pale mitochondria, substantial numbers of terminals in W-cell rich areas were found to contain dark mitochondria. Synaptic vesicles, although consistently round, were typically smaller in terminals with dark mitochondria than in those with pale mitochondria. These findings indicate a diversity among terminals of W-cells and suggest that such terminals cannot be distinguished on the basis of limited morphological criteria.

Keywords

MitochondriaGanglion cell projectionsHorseradish peroxidaseSynaptic vesicles
Type
Research Articles
Information
Visual Neuroscience , Volume 13 , Issue 3 , May 1996 , pp. 449 - 460
Copyright
Copyright © Cambridge University Press 1996

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