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Batroxobin can improve the efficacy of combination therapy for profound sudden sensorineural hearing loss greater than but not less than 100 dB HL

Published online by Cambridge University Press:  31 August 2023

Li Zhu Jiang  and
Wen Qi Zuo Open the ORCID record for Wen Qi Zuo [Opens in a new window]
Li Zhu Jiang
Affiliation:
Department of Otolaryngology, First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China
Wen Qi Zuo*
Affiliation:
Department of Otolaryngology, First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China
*
Corresponding author: Wen Qi Zuo; Email: zuowenqi2023@sina.com
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Abstract

Objective

To investigate the effects of combination therapy with and without batroxobin, and the frequency of batroxobin use on the prognosis of profound sudden sensorineural hearing loss.

Methods

Hearing recovery in the batroxobin group (231 patients) and non-batroxobin group (56 patients) was compared. The correlation between the number of times batroxobin was used and hearing recovery was analysed.

Results

The decrease in hearing threshold and overall improvement rate in the batroxobin group with hearing loss exceeding 100 dB HL was significantly higher than that in the non-batroxobin group. There was no linear correlation between the number of times batroxobin was used and the overall improvement rate. Using batroxobin two to three times achieved a therapeutic effectiveness plateau.

Conclusion

Batroxobin can improve the efficacy of combination therapy for profound sudden sensorineural hearing loss exceeding 100 dB HL, and using batroxobin two to three times yields the maximum overall improvement rate.

Keywords

Batroxobinsudden deafnesssensorineural hearing losstherapyprognosis
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 138 , Issue 3 , March 2024 , pp. 270 - 275
Copyright
Copyright © The Author(s), 2023. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Li Zhu Jiang takes responsibility for the integrity of the content of the paper

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