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Dementia and ‘borderline dementia’ in Britain: 8-year incidence and post-screening outcomes

Published online by Cambridge University Press:  09 July 2009

D. Clarke ,
K. Morgan ,
J. Lilley ,
T. Arie ,
R. Jones ,
J. Waite  and
R. Prettyman
D. Clarke
Affiliation:
Department of Health Care of the Elderly, The Medical School, University of Nottingham
K. Morgan*
Affiliation:
Department of Health Care of the Elderly, The Medical School, University of Nottingham
J. Lilley
Affiliation:
Department of Health Care of the Elderly, The Medical School, University of Nottingham
T. Arie
Affiliation:
Department of Health Care of the Elderly, The Medical School, University of Nottingham
R. Jones
Affiliation:
Department of Health Care of the Elderly, The Medical School, University of Nottingham
J. Waite
Affiliation:
Department of Health Care of the Elderly, The Medical School, University of Nottingham
R. Prettyman
Affiliation:
Department of Health Care of the Elderly, The Medical School, University of Nottingham
*
1Address for correspondence: Dr Kevin Morgan, Department of Health Care for Elderly People, University of Sheffield, Community Sciences Centre, Northern General Hospital, Sheffield S5 7AU.
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Synopsis

Survivors from a nationally representative sample of elderly people originally screened in 1985 were reassessed in 1989 and again in 1993. On each occasion respondents were rated as cognitively impaired, borderline impaired or unimpaired (using a brief information/orientation scale), with the validity of these ratings assessed in subsequent clinical interviews. Where follow-up screening was not possible, information was derived from death certificates and hospital case-notes. Over 8 years (1985–93) the overall incidence rate per person–year at risk was 1·58%, giving age-specific rates of 0·72, 1·32, 1·63, 3·46, 2·55 and 1·41% for the age groups 65–69, 70–74, 75–79, 80–84, 85–89 and ≥ 90 respectively. Of 43 individuals classified at screening as borderline impaired in 1985 and 1989, 19 were diagnosed as demented at clinical interviews conducted within 16 weeks of screening. Four-year follow-ups among the remaining 24 showed that 15 had died, while 6 showed a worsened cognitive status. Controlling for both age and sex, aggregated 4-year mortality was significantly higher among those defined at screening in 1985 and 1989 as either impaired or borderline, when compared with the unimpaired.

Type
Original Articles
Information
Psychological Medicine , Volume 26 , Issue 4 , July 1996 , pp. 829 - 835
Copyright
Copyright © Cambridge University Press 1996

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