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The effect of injection of 1:100 000 adrenaline solution in the pterygopalatine fossa on intra-operative bleeding during endoscopic sinonasal surgical procedures in chronic sinusitis: a blinded clinical trial

Published online by Cambridge University Press:  17 January 2024

Sevil Nasirmohtaram Open the ORCID record for Sevil Nasirmohtaram [Opens in a new window] ,
Mir Mohammad Jalali Open the ORCID record for Mir Mohammad Jalali [Opens in a new window] ,
Ali Faghih Habibi  and
Maliheh Akbarpour Open the ORCID record for Maliheh Akbarpour [Opens in a new window]
Sevil Nasirmohtaram
Affiliation:
Otorhinolaryngology Research Center, Department of Otolaryngology and Head and Neck Surgery, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Mir Mohammad Jalali
Affiliation:
Otorhinolaryngology Research Center, Department of Otolaryngology and Head and Neck Surgery, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Ali Faghih Habibi
Affiliation:
Otorhinolaryngology Research Center, Department of Otolaryngology and Head and Neck Surgery, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Maliheh Akbarpour*
Affiliation:
Otorhinolaryngology Research Center, Department of Otolaryngology and Head and Neck Surgery, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
*
Corresponding author: Maliheh Akbarpour; Email: akbarpour_malihe@yahoo.com
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Abstract

Objective

Rhinosinusitis is one of the most common reasons for a visit to otolaryngology clinics. Some patients are candidates for sinus surgery. Infiltration of 1:100 000 adrenaline in the pterygopalatine fossa was studied, with the aim of evaluating the effect on bleeding in the surgical field.

Methods

This double-blind clinical trial was conducted in 2021–2022 on 40 candidates for endoscopic sinus surgery. For each patient, one side of the pterygopalatine fossa was randomly selected to be infiltrated with a vasoconstrictor. Surgical field bleeding on each side was evaluated.

Results

Blood loss was 35.8 ± 20.9 ml in the study group and 38.4 ± 23.7 ml for the control group, with no statistically significant difference between groups (p = 0.49). In addition, there was no difference between the two groups in terms of the surgical field based on Boezaart scores.

Conclusion

Although there are some recommendations on the usage of vasoconstrictors via the pterygopalatine foramen, debate remains.

Keywords

Paranasal sinusesbleedingpterygopalatine fossaendoscope
Type
Main Article
Information
The Journal of Laryngology & Otology , First View , pp. 1 - 4
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Maliheh Akbarpour takes responsibility for the integrity of the content of the paper

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