Hostname: page-component-848d4c4894-p2v8j Total loading time: 0.001 Render date: 2024-05-30T18:09:41.937Z Has data issue: false hasContentIssue false

Perceptions of the meaning of life among Korean patients with advanced cancer: A mixed-methods study

Published online by Cambridge University Press:  26 August 2022

Su-Jin Koh
Affiliation:
Department of Hematology and Oncology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea
Kyung-Ah Kang
Affiliation:
College of Nursing, Sahmyook University, Seoul, Korea
Hyeyeong Kim
Affiliation:
Department of Hematology and Oncology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea
Jaekyung Cheon
Affiliation:
Department of Medical Oncology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea
Hyeon-Su Im
Affiliation:
Department of Hematology and Oncology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea
Jae-Hon Lee
Affiliation:
Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
Minsu Ock
Affiliation:
Department of Hematology and Oncology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea
Juhee Cho
Affiliation:
Cancer Education Center, Samsung Comprehensive Cancer Center, Seoul, Korea and Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Korea
Eun-Hye Lee*
Affiliation:
College of Nursing, Sahmyook University, Seoul, Korea
*
Author for correspondence: Eun-Hye Lee, College of Nursing, Sahmyook University, 815, Hwarang-ro, Nowon-gu, Seoul 01795, Korea. E-mail: leeeh@syu.ac.kr

Abstract

Objective

This study aimed to explore perceptions of the meaning of life among Korean patients living with advanced cancer.

Method

The study employed a mixed-methods design, and 16 participants were included in the analysis. Qualitative data gathered from in-depth interviews were analyzed using Colaizzi's phenomenological method. Quantitative survey data were analyzed using descriptive statistics, the Mann–Whitney U test, the Kruskal–Wallis test, and Spearman's ρ correlation.

Results

Participants experienced both the existence of meaning and the will to find meaning in terms of four categories: “interpersonal relationships based on attachment and cohesion” (three themes — family as the core meaning of one's life, supportive and dependent interconnectedness with significant others, and existential responsibility embedded in familism), “therapeutic relationships based on trust” (one theme — communication and trust between the patient and medical staff), “optimism” (two themes — positivity embodied through past experiences and a positive attitude toward the current situation), and “a sense of purpose with advanced cancer” (two themes — the will to survive and expectations for the near future). The meaning in life questionnaire (MLQ) and the purpose in life scale (PIL) showed a significant positive correlation tendency with the functional assessment of chronic illness therapy-spiritual well-being scale (FACIT-Sp). The patient health questionnaire (PHQ-9) showed significant negative correlation tendency with both the MLQ-presence of meaning (MLQ-PM) and PIL-Initiative (PIL-I) questionnaires.

Significance of results

Finding meaning in life helps advanced cancer patients realize their will to live. It also acts as a coping mechanism that palliates negative experiences in the fight against the disease. In particular, among advanced cancer patients in the Korean culture, the dynamics of relationships with family and medical staff was a key axis that instilled optimism and will to live. These results suggest that considering the meaning of life in advanced cancer patients by reflecting Korean culture in the treatment process improves the quality of care.

Type
Original Article
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Ahmadi, F, Park, J, Kim, KM, et al. (2016) Exploring existential coping resources: The perspective of Koreans with cancer. Journal of Religion and Health 55(6), 20532068.10.1007/s10943-016-0219-6CrossRefGoogle ScholarPubMed
Akechi, T (2012) Psychotherapy for depression among patients with advanced cancer. Japanese Journal of Clinical Oncology 42(12), 11131119.10.1093/jjco/hys152CrossRefGoogle ScholarPubMed
Ando, M, Morita, T, Akechi, T, et al. (2010) Efficacy of short-term life-review interviews on the spiritual well-being of terminally ill cancer patients. Journal of Pain and Symptom Management 39(6), 9931002.10.1016/j.jpainsymman.2009.11.320CrossRefGoogle ScholarPubMed
Applebaum, AJ, Stein, EM, Lord-Bessen, J, et al. (2012) Factors associated with attrition from a randomized controlled trial of meaning-centered group psychotherapy for patients with advanced cancer. Psycho-Oncology 21(11), 11951204.10.1002/pon.2013CrossRefGoogle ScholarPubMed
Applebaum, AJ, Stein, EM, Lord-Bessen, J, et al. (2014) Optimism, social support, and mental health outcomes in patients with advanced cancer. Psycho-Oncology 23(3), 299306.10.1002/pon.3418CrossRefGoogle ScholarPubMed
Ashrafian, S, Feizollahzadeh, H, Rahmani, A, et al. (2018) The unmet needs of the family caregivers of patients with cancer visiting a referral hospital in Iran. Asia-Pacific Journal of Oncology Nursing 5(3), 342.10.4103/apjon.apjon_7_18CrossRefGoogle ScholarPubMed
Bishop, FL (2015) Using mixed methods research designs in health psychology: An illustrated discussion from a pragmatist perspective. British Journal of Health Psychology 20(1), 520.10.1111/bjhp.12122CrossRefGoogle ScholarPubMed
Bovero, A, Botto, R, Adriano, B, et al. (2019) Exploring demoralization in end-of-life cancer patients: Prevalence, latent dimensions, and associations with other psychosocial variables. Palliative & Supportive Care 17(5), 596603.10.1017/S1478951519000191CrossRefGoogle ScholarPubMed
Breitbart, W, Pessin, H, Rosenfeld, B, et al. (2015) Meaning-centered group psychotherapy: An effective intervention for improving psychological well-being in patients with advanced cancer. Journal of Clinical Oncology 33(7), 749.10.1200/JCO.2014.57.2198CrossRefGoogle ScholarPubMed
Breitbart, W, Rosenfeld, B, Pessin, H, et al. (2018) Individual meaning-centered psychotherapy for the treatment of psychological and existential distress: A randomized controlled trial in patients with advanced cancer. Cancer 124(15), 32313239.10.1002/cncr.31539CrossRefGoogle ScholarPubMed
Campbell, CL and Campbell, LC (2012) A systematic review of cognitive behavioral interventions in advanced cancer. Patient Education and Counseling 89(1), 1524.10.1016/j.pec.2012.06.019CrossRefGoogle ScholarPubMed
Caruso, R, Nanni, MG, Rodin, G, et al. (2020) Effectiveness of a brief manualized intervention, managing cancer and living meaningfully (CALM), adapted to the Italian cancer care setting: Study protocol for a single-blinded randomized controlled trial. Contemporary Clinical Trials Communications 20, 100661.10.1016/j.conctc.2020.100661CrossRefGoogle Scholar
Chochinov, HM, Hack, T, Hassard, T, et al. (2005) Dignity therapy: A novel psychotherapeutic intervention for patients near the end of life. Journal of Clinical Oncology 23(24), 55205525.10.1200/JCO.2005.08.391CrossRefGoogle ScholarPubMed
Chochinov, HM, Kristjanson, LJ, Breitbart, W, et al. (2011) Effect of dignity therapy on distress and end-of-life experience in terminally ill patients: A randomised controlled trial. The Lancet Oncology 12(8), 753762.10.1016/S1470-2045(11)70153-XCrossRefGoogle Scholar
Choi, JH (2018) The Understanding of Korean Family. Seoul: Jungmin Publishing.Google Scholar
Colaizzi, PF (1978) Psychological research as the phenomenologist views it. In Valle, RS and King, M (eds.), Existential-Phenomenological Alternatives for Psychology. Oxford University Press, 6.Google Scholar
Cormack, C and Mazanec, P (2019) Cultural Considerations in Palliative Care. In Oxford Textbook of Palliative Nursing, p. 469.Google Scholar
Costas-Muñiz, R, Torres-Blasco, N, Castro-Figueroa, EM, et al. (2020) Meaning-centered psychotherapy for Latino patients with advanced cancer: Cultural adaptation process. Journal of Palliative Medicine 23(4), 489497.10.1089/jpm.2019.0423CrossRefGoogle ScholarPubMed
Creswell, JW, Klassen, AC, Plano Clark, VL, et al. (2011) Best Practices for Mixed Methods Research in the Health Sciences. Bethesda, MD: National Institutes of Health, p. 541545.Google Scholar
Diaz-Frutos, D, Baca-Garcia, E, García-Foncillas, J, et al. (2016) Predictors of psychological distress in advanced cancer patients under palliative treatments. European Journal of Cancer Care 25(4), 608615.10.1111/ecc.12521CrossRefGoogle ScholarPubMed
Emslie, C, Browne, S, MacLeod, U, et al. (2009) 'Getting through' not ‘going under': A qualitative study of gender and spousal support after diagnosis with colorectal cancer. Social Science & Medicine 68(6), 11691175.10.1016/j.socscimed.2009.01.004CrossRefGoogle ScholarPubMed
Fang, SY, Chang, HT and Shu, BC (2015) The moderating effect of perceived partner empathy on body image and depression among breast cancer survivors. Psycho-Oncology 24(12), 18151822.10.1002/pon.3868CrossRefGoogle ScholarPubMed
Finck, C, Barradas, S, Zenger, M, et al. (2018) Quality of life in breast cancer patients: Associations with optimism and social support. International Journal of Clinical and Health Psychology 18(1), 2734.10.1016/j.ijchp.2017.11.002CrossRefGoogle ScholarPubMed
Frankl, VE (1984) Search for Meaning. Milwaukee, WI: Mount Mary College.Google Scholar
Hales, S, Lo, C and Rodin, G (2015) Managing Cancer and Living Meaningfully (CALM) Therapy, Chap. 62, pp. 487–491.Google Scholar
Han, JY, Kim, E, Lee, YI, et al. (2019) A longitudinal investigation of empathic exchanges in online cancer support groups: Message reception and expression effects on patients’ psychosocial health outcomes. Journal of Health Communication 24(6), 615623.10.1080/10810730.2019.1644401CrossRefGoogle ScholarPubMed
Hedayati, MM and Khazaei, MM (2014) An investigation of the relationship between depression, meaning in life and adult hope. Procedia – Social and Behavioral Sciences 114, 598601.10.1016/j.sbspro.2013.12.753CrossRefGoogle Scholar
Henry, M, Cohen, SR, Lee, V, et al. (2010) The meaning-making intervention (MMi) appears to increase meaning in life in advanced ovarian cancer: A randomized controlled pilot study. Psycho-Oncology 19(12), 13401347.10.1002/pon.1764CrossRefGoogle ScholarPubMed
Henson, LA, Edmonds, P, Johnston, A, et al. (2020) Population-based quality indicators for end-of-life cancer care: A systematic review. JAMA Oncology 6(1), 142150.10.1001/jamaoncol.2019.3388CrossRefGoogle ScholarPubMed
Ho, ZJM, Krishna, LKR, Goh, C, et al. (2013) The physician-patient relationship in treatment decision making at the end of life: A pilot study of cancer patients in a southeast Asian society. Palliative & Supportive Care 11(1), 13.Google Scholar
Holwerda, N, Sanderman, R, Pool, G, et al. (2013) Do patients trust their physician? The role of attachment style in the patient-physician relationship within one year after a cancer diagnosis. Acta Oncologica 52(1), 110117.10.3109/0284186X.2012.689856CrossRefGoogle ScholarPubMed
Hunter, MJ, Davis, PJ and Tunstall, JR (2006) The influence of attachment and emotional support in end-stage cancer. Psychooncology: Journal of the Psychological, Social and Behavioral Dimensions of Cancer 15(5), 431444.10.1002/pon.965CrossRefGoogle ScholarPubMed
Kim, KO and Kim, J-A (2019) Concept analysis of fighting spirit in Korean patients with cancer. Korean Journal of Adult Nursing 31(1), 5060.10.7475/kjan.2019.31.1.50CrossRefGoogle Scholar
Kim, H, Jung, S, Ko, Y, et al. (2001) Reliability & validity of Korean version of 'Purpose in life (PIL) test' scale. Journal of Korean Association of Social Psychiatry 6(2), 155165.Google Scholar
Lee, V and Loiselle, CG (2012) The salience of existential concerns across the cancer control continuum. Palliative & Supportive Care 10(2), 123.10.1017/S1478951511000745CrossRefGoogle ScholarPubMed
Lee, MK and Yun, YH (2018) Family functioning predicts end-of-life care quality in patients with cancer: Multicenter prospective cohort study. Cancer Nursing 41(3), E1E10.10.1097/NCC.0000000000000495CrossRefGoogle ScholarPubMed
Lee, S-M, Song, HR, Lee, WJ, et al. (2012) Characteristics of transitional period of Korean family and family policy. Journal of Korean Home Management Association 30(6), 183199.10.7466/JKHMA.2012.30.6.183CrossRefGoogle Scholar
Lee, S, Huh, Y and Kim, J (2014) Finding optimal cut off points of the Korean version of the patient health questionnaire-9 (PHQ-9) for screening depressive disorders. Mood & Emotion 12(1), 3236.Google Scholar
Lee, J, Chin, M and Sung, M (2020) How has COVID-19 changed family life and well-being in Korea? Journal of Comparative Family Studies 51(3–4), 301313.10.3138/jcfs.51.3-4.006CrossRefGoogle Scholar
Leng, J, Lui, F, Chen, A, et al. (2018) Adapting meaning-centered psychotherapy in advanced cancer for the Chinese immigrant population. Journal of Immigrant and Minority Health 20(3), 680686.10.1007/s10903-017-0591-7CrossRefGoogle ScholarPubMed
Li, HC, Richardson, A, Speck, P, et al. (2014) Conceptualizations of dignity at the end of life: Exploring theoretical and cultural congruence with dignity therapy. Journal of Advanced Nursing 70(12), 29202931.10.1111/jan.12455CrossRefGoogle ScholarPubMed
Lincoln, YS and Guba, EG (1985) Naturalistic Inquiry. Newberry Park, CA: Sage.10.1016/0147-1767(85)90062-8CrossRefGoogle Scholar
Liu, Y, Yang, J, Huo, D, et al. (2018) Disclosure of cancer diagnosis in China: The incidence, patients’ situation, and different preferences between patients and their family members and related influence factors. Cancer Management and Research 10, 2173.10.2147/CMAR.S166437CrossRefGoogle Scholar
Lo, C, Hales, S, Jung, J, et al. (2014) Managing cancer and living meaningfully (CALM): Phase 2 trial of a brief individual psychotherapy for patients with advanced cancer. Palliative Medicine 28(3), 234242.10.1177/0269216313507757CrossRefGoogle ScholarPubMed
Lo, C, Hales, S, Rydall, A, et al. (2015) Managing cancer and living meaningfully: Study protocol for a randomized controlled trial. BMC Trials 16(1), 18.Google ScholarPubMed
Malouff, JM and Schutte, NS (2017) Can psychological interventions increase optimism? A meta-analysis. The Journal of Positive Psychology 12(6), 594604.10.1080/17439760.2016.1221122CrossRefGoogle Scholar
Miyashita, M, Kawakami, S, Kato, D, et al. (2015) The importance of good death components among cancer patients, the general population, oncologists, and oncology nurses in Japan: Patients prefer “fighting against cancer”. Supportive Care in Cancer 23(1), 103110.10.1007/s00520-014-2323-zCrossRefGoogle Scholar
Mok, E, Lau, KP, Lai, T, et al. (2012) The meaning of life intervention for patients with advanced-stage cancer: development and pilot study. Oncology Nursing Forum 39(6), E480E488.10.1188/12.ONF.E480-E488CrossRefGoogle Scholar
Nam, SI, Nam, H, Lee, J, et al. (2019) A study on moderating effect of meaning in life in relationship between ageing anxiety and depression for young-old and old-old in Korea. Korea Academy of Mental Health Social Work 47(2), 6796.10.24301/MHSW.2019.06.47.2.67CrossRefGoogle Scholar
Nicholls, W, Hulbert-Williams, N and Bramwell, R (2014) The role of relationship attachment in psychological adjustment to cancer in patients and caregivers: A systematic review of the literature. Psycho-Oncology 23(10), 10831095.10.1002/pon.3664CrossRefGoogle ScholarPubMed
Nissim, R, Freeman, E, Lo, C, et al. (2012) Managing cancer and living meaningfully (CALM): A qualitative study of a brief individual psychotherapy for individuals with advanced cancer. Palliative Medicine 26(5), 713721.10.1177/0269216311425096CrossRefGoogle Scholar
Okuyama, T, Akechi, T, Mackenzie, L, et al. (2017) Psychotherapy for depression among advanced, incurable cancer patients: A systematic review and meta-analysis. Cancer Treatment Reviews 56, 1627.10.1016/j.ctrv.2017.03.012CrossRefGoogle ScholarPubMed
Peterman, AH, Fitchett, G, Brady, MJ, et al. (2002) Measuring spiritual well-being in people with cancer: The functional assessment of chronic illness therapy—spiritual well-being scale (FACIT-Sp). Annals of Behavioral Medicine 24(1), 4958.10.1207/S15324796ABM2401_06CrossRefGoogle ScholarPubMed
Radina, ME, Armer, JM and Stewart, BR (2014) Making self-care a priority for women at risk of breast cancer-related lymphedema. Journal of Family Nursing 20(2), 226249.10.1177/1074840714520716CrossRefGoogle ScholarPubMed
Rodin, G, Lo, C, Rydall, A, et al. (2018) Managing cancer and living meaningfully (CALM): A randomized controlled trial of a psychological intervention for patients with advanced cancer. Journal of Clinical Oncology 36(23), 2422.10.1200/JCO.2017.77.1097CrossRefGoogle Scholar
Rodin, G, Malfitano, C, Rydall, A, et al. (2020a) Emotion and symptom-focused engagement (EASE): A randomized phase II trial of an integrated psychological and palliative care intervention for patients with acute leukemia. Supportive Care in Cancer 28(1), 163176.10.1007/s00520-019-04723-2CrossRefGoogle ScholarPubMed
Rodin, G, An, E, Shnall, J, et al. (2020b) Psychological interventions for patients with advanced disease: Implications for oncology and palliative care. Journal of Clinical Oncology 38(9), 885904.10.1200/JCO.19.00058CrossRefGoogle ScholarPubMed
Rosenfeld, B, Saracino, R, Tobias, K, et al. (2017) Adapting meaning-centered psychotherapy for the palliative care setting: Results of a pilot study. Palliative Medicine 31(2), 140146.10.1177/0269216316651570CrossRefGoogle ScholarPubMed
Scheffold, K, Philipp, P, Vehling, S, et al. (2019) Spiritual well-being mediates the association between attachment insecurity and psychological distress in advanced cancer patients. Supportive Care in Cancer 27(11), 43174325.10.1007/s00520-019-04744-xCrossRefGoogle ScholarPubMed
Sethi, R, Rodin, G and Hales, S (2020) Psychotherapeutic approach for advanced illness: Managing cancer and living meaningfully (CALM) therapy. American Journal of Psychotherapy 73(4), 119124.10.1176/appi.psychotherapy.20190050CrossRefGoogle ScholarPubMed
Shim, K and Shin, H (2019) Exploring parenting decisions among South Korean mothers with preschool-age children. Journal of Comparative Family Studies 50(1), 3350.10.3138/jcfs.022-2018CrossRefGoogle Scholar
Simonelli, LE, Fowler, J, Maxwell, GL, et al. (2008) Physical sequelae and depressive symptoms in gynecologic cancer survivors: Meaning in life as a mediator. Annals of Behavioral Medicine 35(3), 275284.10.1007/s12160-008-9029-8CrossRefGoogle ScholarPubMed
Su, J-A, Yeh, DC, Chang, CC, et al. (2017) Depression and family support in breast cancer patients. Neuropsychiatric Disease and Treatment 13, 2389.10.2147/NDT.S135624CrossRefGoogle ScholarPubMed
Surbone, A (2008) Cultural aspects of communication in cancer care. Supportive Care in Cancer 16(3), 235240.10.1007/s00520-007-0366-0CrossRefGoogle ScholarPubMed
Turkdogan, T, Duru, E and Balkis, M (2019) Circumplex model of family functioning in Turkish culture: Western family systems model in a Eurasian country. Journal of Comparative Family Studies 50(2), 183199.10.3138/jcfs.50.2.005CrossRefGoogle Scholar
Vehling, S, Tian, Y, Malfitano, C, et al. (2019) Attachment security and existential distress among patients with advanced cancer. Journal of Psychosomatic Research 116, 9399.10.1016/j.jpsychores.2018.11.018CrossRefGoogle ScholarPubMed
Viitala, A, Saukkonen, M, Lehto, JT, et al. (2018) The coping and support needs of incurable cancer patients. Journal of Hospice & Palliative Nursing 20(2), 187194.10.1097/NJH.0000000000000427CrossRefGoogle ScholarPubMed
Vuksanovic, D, Green, HJ, Dyck, M, et al. (2017) Dignity therapy and life review for palliative care patients: A randomized controlled trial. Journal of Pain and Symptom Management 53(2), 162170.e1.10.1016/j.jpainsymman.2016.09.005CrossRefGoogle ScholarPubMed
Wessels, H, de Graeff, A, Wynia, K, et al. (2010) Gender-related needs and preferences in cancer care indicate the need for an individualized approach to cancer patients. The Oncologist 15(6), 648.10.1634/theoncologist.2009-0337CrossRefGoogle ScholarPubMed
Wise, M, Marchand, LR, Roberts, LJ, et al. (2018) Suffering in advanced cancer: A randomized control trial of a narrative intervention. Journal of Palliative Medicine 21(2), 200207.10.1089/jpm.2017.0007CrossRefGoogle Scholar
Won, D, Kim, K and Kwon, S-J (2005) Validation of the Korean version of meaning in life questionnaire. The Korean Journal of Health Psychology 10(2), 211225.Google Scholar
Yang, N, Xiao, H, Cao, Y, et al. (2018) Influence of oncology nurses’ empathy on lung cancer patients’ cellular immunity. Psychology Research and Behavior Management 11, 279.10.2147/PRBM.S168649CrossRefGoogle ScholarPubMed
Yang, J, Choi, M, Choi, J, et al. (2020) Supervised physical rehabilitation in the treatment of patients with advanced cancer: A systematic review and meta-analysis. Journal of Korean Medical Science 35(29), 279287.10.3346/jkms.2020.35.e242CrossRefGoogle Scholar
Yu, J and Ha, JH (2015) Expected promising future of psychoanalysis in Korea. Psychoanalysis 26(3), 7581.Google Scholar
Yu, M-Y, Hong, O-S and Seetoo, AD (2003) Uncovering factors contributing to under-utilization of breast cancer screening by Chinese and Korean women living in the United States. Ethnicity & Disease 13(2), 213219.Google ScholarPubMed
Supplementary material: PDF

Koh et al. supplementary material

Koh et al. supplementary material 1

Download Koh et al. supplementary material(PDF)
PDF 328.4 KB
Supplementary material: File

Koh et al. supplementary material

Koh et al. supplementary material 2

Download Koh et al. supplementary material(File)
File 26.8 KB