In the light of the emerging global ecumene there is an ongoing intellectual discourse that focuses on the quest for a reorientation of political theorizing. It challenges the more or less canonized approaches to the understanding of political life and thought that dominate Western mainstream political and social science. This essay critically explores the epistemological assumptions underlying the prevalent paradigm of socio-political analysis, and points out its weakness in coming to grips with the multi-civilizational cosmos of human self-understanding which makes up the historico-political world. It argues that a genuine hermeneutical science is needed in order to restate the meaningful pattern of human self-interpretation across cultures and civilizations in its historical depth and global reach. It takes as its starting point the rise of the great civilizations in the axial times and their respective visions of order which still shape modernity. These post-axial visions, various as they were in appearance and content, merged with political power to provide the meaning-creating symbolic forms of societal self-understanding, thus providing society with a logic of order. This essay defines the common ground of the intercivilizational modality of human existence in history and society as the proper subject of comparative political theorizing, insofar as it intends to bring to our attention the essence of the political in all of its historical modalities.