Ford soybean yields and weed yields were studied under combinations of tillage treatments, 3-amino-2,5-dichlorobenzoic acid (amiben) applications, hand weedings, and row spacings on irrigated and non-irrigated locations in Nebraska during 1961 and 1962. Soybean yields increased and weed yields decreased with tillage, amiben applications, hand weedings, and narrow-row spacing of soybeans. Combinations of these weed control treatments gave more dependable results than any one alone. Each 86 lb/A of weeds present produced an average soybean yield reduction of 1 bu/A. Advantages of growing soybeans with amiben applications in 10-inch rows as compared to 40-inch rows are: (a) an average soybean yield increase of 39%, (b) elimination or reduction of tillage (c) a 50 to 75% reduction in amiben application rate, and (d) little or no soybean injury from the lower rates of amiben required in the 10-inch rows.