The nature and behaviour of sediment beneath glaciers influences how they flow and respond to changing environmental conditions. The difficulty of accessing the bed of current glaciers is a key constraint to studying the processes involved. This paper explores an alternative approach by relating sediments under the beds of former mid-latitude ice sheets to changing ice behaviour during a glacial cycle. The paper focuses on the partly marine-based Pleistocene British-Irish ice sheet in the Clyde basin, Scotland. A three-dimensional computation of subsurface glacial sediment distribution is derived from 1260 borehole logs. Sediment distribution is linked to an empirically based reconstruction of ice-sheet evolution, permitting identification of distinctive phases of sedimentation. Maximum sediment mobilization and till deposition (~0.04ma_1) occurred during ice advance into the basin from adjacent uplands. Transport distances were generally short. Subglacial processes were influenced locally by the relative stiffness of pre-existing sediments, the permeability of the sub-till lithology, and topography; the resulting mean till thickness is 7.7 m with a high standard deviation of 7.0 m. In places, focused till deposition sealed pre-existing permeable substrates, promoting lower effective pressures. Sediment remobilization by meltwater was a key process as ice margins retreated through the, basin.