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Relationship between the depression levels and nutritional statuses of advanced stage cancer patients

Published online by Cambridge University Press:  30 September 2021

Dilek Yildirim*
Affiliation:
Department of Nursing, University Faculty of Health Sciences, Istanbul Aydin University, Istanbul, Turkey
*
Author for correspondence: Dilek Yildirim, Department of Nursing, University Faculty of Health Sciences, Istanbul Aydin University, Florya Campus (Halit Aydın Campus), Inönü Street No: 38 Sefaköy - Kucukcekmece, Istanbul, Turkey. E-mails: dilekyildirim@aydin.edu.tr; dilekaticiyildirim@gmail.com

Abstract

Objective

This study aimed to determine the depression and nutritional statuses of advanced stage cancer patients and investigate the relationship between depression and malnutrition.

Method

The descriptive, cross-sectional, and correlational study was conducted with 245 patients with advanced cancer. The data were collected by using an Information Form, the Visual Analog Scale, the NRS-2002-Nutritional Risk Score, and the Beck Depression Inventory.

Results

The mean NRS-2002 score of the patients was 2.22, and when the cutoff value was accepted as 3, it was determined that 39.2% of the patients had malnutrition. The mean Beck Depression Inventory score of the patients was 35.06, and they were found to experience severe depression. There was a positive and significant relationship between the NRS-2002 scores and the Beck Depression Inventory scores (r = 0.409; p < 0.001).

Significance of results

These results showed that there was a strong relationship between the depression and malnutrition levels of advanced stage cancer patients. Deterioration in the nutritional status of the advanced stage cancer patients was associated with a significant worsening effect in terms of depression and pain.

Type
Original Article
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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References

Alacacioglu, A, Tarhan, O, Alacacioglu, I, et al. (2013) Depression and anxiety in cancer patients and their relatives. Journal of BUON 18(3), 767774.Google ScholarPubMed
Arends, J, Bachmann, P, Baracos, V, et al. (2017) ESPEN guidelines on nutrition in cancer patients. Clinical Nutrition 36(1), 1148. doi:10.1016/j.clnu.2016.07.015.CrossRefGoogle ScholarPubMed
Attar, A, Malka, D, Sabate, JM, et al. (2012) Malnutrition is high and underestimated during chemotherapy in gastrointestinal cancer: An AGEO prospective cross-sectional multicenter study. Nutrition and Cancer 64(4), 535542.CrossRefGoogle ScholarPubMed
Beck, AT, Steer, RA and Carbin, MG (1988) Psychometric properties of the beck depression inventory: Twenty-five years of evaluation. Clinical Psychology Review 8(1), 77100.CrossRefGoogle Scholar
Bener, A, Alsulaiman, R, Doodson, L, et al. (2017) Depression, hopelessness and social support among breast cancer patients: In highly endogamous population. Asian Pacific Journal of Cancer Prevention 18(7), 18891896. doi:10.22034/APJCP.2017.18.7.1889.Google Scholar
Bolayır, B (2014). Evaluation of Validity and Reliability of Nutritional Assessment Test NRS-2002 (Nutritional Risk Screening-2002) in Hospitalized Patients (Medical specialty thesis). Hacettepe University, Faculty of Medicine, Ankara.Google Scholar
Bortolato, B, Hyphantis, TN, Valpione, S, et al. (2017) Depression in cancer: The many biobehavioral pathways driving tumor progression. Cancer Treatment Reviews 52, 5870. doi:10.1016/j.ctrv.2016.11.004.CrossRefGoogle ScholarPubMed
Bossola, M (2015) Nutritional interventions in head and neck cancer patients undergoing chemoradiotherapy: A narrative review. Nutrients 7(1), 265276. doi:10.3390/nu7010265.CrossRefGoogle ScholarPubMed
Bray, F, Ferlay, J, Soerjomataram, I, et al. (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians 68(6), 394424. doi:10.3322/caac.21492.Google ScholarPubMed
Britton, B, Baker, A, Clover, K, et al. (2017) Heads up: A pilot trial of a psychological intervention to improve nutrition in head and neck cancer patients undergoing radiotherapy. European Journal of Cancer Care 26(4), e12502. doi:10.1111/ecc.12502.CrossRefGoogle ScholarPubMed
Caruso, R, Nanni, MG, Riba, M, et al. (2017) Depressive spectrum disorders in cancer: Prevalence, risk factors and screening for depression: A critical review. Acta Oncologica 56(2), 146155. doi:10.1080/0284186X.2016.1266090.CrossRefGoogle ScholarPubMed
Chabowski, M, Polański, J, Jankowska-Polańska, B, et al. (2018) Is nutritional status associated with the level of anxiety, depression and pain in patients with lung cancer? Journal of Thoracic Disease 10(4), 23032310. doi:10.21037/jtd.2018.03.108.CrossRefGoogle ScholarPubMed
Choi, S and Ryu, E (2018) Effects of symptom clusters and depression on the quality of life in patients with advanced lung cancer. European Journal of Cancer Care 27(1), e12508. doi:10.1111/ecc.12508.CrossRefGoogle ScholarPubMed
De Ulíbarri, JI, González-Madroño, A, de Villar, NG, et al. (2005) CONUT: A tool for controlling nutritional status. First validation in a hospital population. Nutricion Hospitalaria 20(1), 3845.Google Scholar
Dos Santos, CA, Rosa, CDOB, Ribeiro, AQ, et al. (2015) Patient-generated subjective global assessment and classic anthropometry: Comparison between the methods in detection of malnutrition among elderly with cancer. Nutricion Hospitalaria 31(1), 384392. doi:10.3305/nh.2015.31.1.7543.Google Scholar
Fearon, K, Strasser, F, Anker, SD, et al. (2011) Definition and classification of cancer cachexia: An international consensus. The Lancet Oncology 12(5), 489495. doi:10.1016/S1470-2045(10)70218-7.CrossRefGoogle Scholar
Gosak, M, Gradišar, K, Kozjek, NR, et al. (2020) Psychological distress and nutritional status in head and neck cancer patients: A pilot study. European Archives of Oto-Rhino-Laryngology 277(4), 12111217. doi:10.1007/s00405-020-05798-y.CrossRefGoogle ScholarPubMed
Gyan, E, Raynard, B, Durand, JP, et al. (2018) Malnutrition in patients with cancer: Comparison of perceptions by patients, relatives, and physicians—results of the NutriCancer2012 study. Journal of Parenteral and Enteral Nutrition 42(1), 255260. doi:10.1177/0148607116 688881.Google ScholarPubMed
Hinz, A, Herzberg, PY, Lordick, F, et al. (2019) Age and gender differences in anxiety and depression in cancer patients compared with the general population. European Journal of Cancer Care 28(5), e13129. doi:10.1111/ecc.13129.CrossRefGoogle ScholarPubMed
Hisli, SN (1988) A study on the validity of the beck depression inventory. Turkish Journal of Psychology 6(22), 118126.Google Scholar
Hong, JS, Wu, LH, Su, L, et al. (2016) Effect of chemoradiotherapy on nutrition status of patients with nasopharyngeal cancer. Nutrition and Cancer 68(1), 6369. doi:10.1080/01635581.2016.1115099.CrossRefGoogle ScholarPubMed
Isenberg-Grzeda, E, Hsu, AJ, Hatzoglou, V, et al. (2015) Palliative treatment of thiamine-related encephalopathy (Wernicke's encephalopathy) in cancer: A case series and review of the literature. Palliative Support Care 13(5), 12411249. doi:10.1017/S1478951514001163.CrossRefGoogle ScholarPubMed
Isenberg-Grzeda, E, Rahane, S, DeRosa, AP, et al. (2016) Wernicke-Korsakoff syndrome in patients with cancer: A systematic review. Lancet Oncology 17(4), e142e148. doi:10.1016/S1470-2045(16)00037-1.CrossRefGoogle ScholarPubMed
Kondrup, J, Allison, SP, Elia, M, et al. (2003) ESPEN guidelines for nutrition screening 2002. Clinical Nutrition 22(4), 415421. doi:10.1016/S0261-5614(03)00098-0.CrossRefGoogle ScholarPubMed
Langius, JA, Twisk, J, Kampman, M, et al. (2016) Prediction model to predict critical weight loss in patients with head and neck cancer during (chemo) radiotherapy. Oral Oncology 52, 9196. doi:10.1016/j.oraloncology.2015.10.021.CrossRefGoogle ScholarPubMed
Lewis, SC (2009) Sample size calculations in clinical research. Journal of Applied Statistics 36(4), 469. doi:10.1080/02664760802366775.CrossRefGoogle Scholar
Li, M, Kennedy, EB, Byrne, N, et al. (2017) Systematic review and meta-analysis of collaborative care interventions for depression in patients with cancer. Psycho-Oncology 26(5), 573587. doi:10.1002/pon.4286.CrossRefGoogle ScholarPubMed
Ma, L, Poulin, P, Feldstain, A, et al. (2013) The association between malnutrition and psychological distress in patients with advanced head-and-neck cancer. Current Oncology 20(6), e554. doi:10.3747/co.20.1651.CrossRefGoogle ScholarPubMed
Massie, MJ (2004) Prevalence of depression in patients with cancer. Journal of the National Cancer Institute Monograph 2004(32), 5771.CrossRefGoogle Scholar
Mohammadzadeh, A and Najafi, M (2020) The comparison of death anxiety, obsession, and depression between muslim population with positive and negative religious coping. Journal of Religion and Health 59(2), 10551064. doi:10.1007/s10943-018-0679-y.CrossRefGoogle ScholarPubMed
Okuyama, T, Akechi, T, Mackenzie, L, et al. (2017) Psychotherapy for depression among advanced, incurable cancer patients: A systematic review and meta-analysis. Cancer Treatment Reviews 56, 1627. doi:10.1016/j.ctrv.2017.03.012.CrossRefGoogle ScholarPubMed
Onishi, H, Sato, I, Uchida, N, et al. (2021) High proportion of thiamine deficiency in referred cancer patients with delirium: A retrospective descriptive study. European Journal of Clinical Nutrition 29. doi:10.1038/s41430-021-00859-9.Google Scholar
Orell-Kotikangas, H, Österlund, P, Saarilahti, K, et al. (2015) NRS-2002 for pre-treatment nutritional risk screening and nutritional status assessment in head and neck cancer patients. Supportive Care in Cancer 23(6), 14951502. doi:0.1007/s00520-014-2500-0.CrossRefGoogle ScholarPubMed
Ostuzzi, G, Matcham, F, Dauchy, S, et al. (2018) Antidepressants for the treatment of depression in people with cancer. Cochrane Database of Systematic Reviews 23(4), CD011006. doi:10.1002/14651858.CD011006.pub3.Google Scholar
Parpa, E, Tsilika, E, Galanos, A, et al. (2019) Depression as mediator and or moderator on the relationship between hopelessness and patients’ desire for hastened death. Supportive Care in Cancer 27(11), 43534358. doi:10.1007/s00520-019-04715-2.CrossRefGoogle ScholarPubMed
Pinho, NB, Martucci, RB, Rodrigues, VD, et al. (2019) Malnutrition associated with nutrition impact symptoms and localization of the disease: Results of a multicentric research on oncological nutrition. Clinical Nutrition 38(3), 12741279. doi:10.1016/j.clnu.2018.05.010. 7.CrossRefGoogle ScholarPubMed
Pitman, A, Suleman, S, Hyde, N, et al. (2018) Depression and anxiety in patients with cancer. BMJ 361, k1415. doi:doi:10.1136/bmj.k1415.CrossRefGoogle ScholarPubMed
Planas, M, Álvarez-Hernández, J, León-Sanz, M, et al. (2016) Prevalence of hospital malnutrition in cancer patients: A sub-analysis of the PREDyCES® study. Supportive Care in Cancer 24(1), 429435.CrossRefGoogle ScholarPubMed
Prevost, V, Joubert, C, Heutte, N, et al. (2014) Assessment of nutritional status and quality of life in patients treated for head and neck cancer. European Annals of Otorhinolaryngology, Head and Neck Diseases 131(2), 113120. doi:10.1016/j.anorl.2013.06.007.CrossRefGoogle ScholarPubMed
Saxton, JM, Scott, EJ, Daley, AJ, et al. (2014) Effects of an exercise and hypocaloric healthy eating intervention on indices of psychological health status, hypothalamic-pituitary-adrenal axis regulation and immune function after early-stage breast cancer: A randomised controlled trial. Breast Cancer Research 16(2), R39. doi:10.1186/bcr3643.CrossRefGoogle ScholarPubMed
Sharif, SP, Lehto, RH, Nia, HS, et al. (2018) Religious coping and death depression in Iranian patients with cancer: Relationships to disease stage. Supportive Care in Cancer 26(8), 25712579. doi:10.1007/s00520-018-4088-2.CrossRefGoogle ScholarPubMed
Zhu, C, Wang, B, Gao, Y, et al. (2018) Prevalence and relationship of malnutrition and distress in patients with cancer using questionnaires. BMC Cancer 18(1), 1272. doi:10.1186/s12885-018-5176-x.CrossRefGoogle ScholarPubMed