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Delirium documentation in hospitalized pediatric patients with cancer

Published online by Cambridge University Press:  01 March 2021

Kelly Lastrapes
Affiliation:
Pediatric Hematology, Oncology and Palliative Care, Department of Pediatrics, Division of Pediatric Hematology/Oncology, Virginia Commonwealth University, Richmond, VA, USA
Malisa Dang
Affiliation:
Department of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA, USA
J. Brian Cassel
Affiliation:
Department of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA, USA
Tamara Orr
Affiliation:
Department of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA, USA
Tracye Proffitt
Affiliation:
Department of Adult Health and Nursing Systems, Virginia Commonwealth University, Richmond, VA, USA
Egidio Del Fabbro*
Affiliation:
Department of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA, USA
*
Author for correspondence: Egidio Del Fabbro, Department of Internal Medicine, Division of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA, USA. E-mail: egidio.delfabbro@vcuhealth.org

Abstract

Objective

Screening tools for delirium are being used more consistently in pediatric critical care. However, screening is not universal, and delirium may be underdiagnosed, misdiagnosed, or undocumented in hospitalized patients. We evaluated the identification and documentation of delirium in pediatric oncology and bone marrow transplant patients.

Method

A retrospective chart review on all hospitalized pediatric oncology and bone marrow transplant patients admitted to an Academic Cancer center between 2013 and 2016. Patients aged less than 21 years of age with active cancer were included. Patients with major psychiatric conditions, developmental delays, or autism were excluded. Data were collected to characterize documentation concerning the identification and diagnosis of delirium.

Results

Of 201 hospitalization records, 54 (26.9%) admissions from 109 unique patients had documentation of delirium. The overall documented incidence of delirium was 3.2% of hospitalizations or 8.2% of unique patients. Patients prescribed opioids and benzodiazepines were more likely to have documentation of delirium. ICD coding under-reported delirium while physician documentation was inaccurate in 26% (53/201) when compared with the chart review.

Significance of results

Delirium was frequently undocumented or miscoded. Implementing a validated, universal screening tool for delirium may improve identification and clinical outcomes.

Type
Original Article
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

*

These authors contributed equally to this work.

References

REFERENCES

American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders, 5th ed. Arlington: American Psychiatric Publishing.Google Scholar
Breitbart, W and Alici, Y (2012) Evidence-based treatment of delirium in patients with cancer. Journal of Clinical Oncology 30(11), 12061214.10.1200/JCO.2011.39.8784CrossRefGoogle ScholarPubMed
Casey, P, Cross, W, Mart, MW, et al. (2019) Hospital discharge data under-reports delirium occurrence: Results from a point prevalence survey of delirium in a major Australian health service. Internal Medicine Journal 49(3), 338344.10.1111/imj.14066CrossRefGoogle Scholar
Combs, D, Rice, SA and Kopp, LM (2014) Incidence of delirium in children with cancer. Pediatric Blood & Cancer 61(11), 20942095.10.1002/pbc.25107CrossRefGoogle ScholarPubMed
Daoud, A, Duff, JP, Joffe, AR, et al. (2014) Diagnostic accuracy of delirium diagnosis in pediatric intensive care: A systematic review. Critical Care (London, England) 18(5), 489.10.1186/s13054-014-0489-xCrossRefGoogle ScholarPubMed
Dupuis, LL, Boodhan, S, Holdsworth, M, et al. (2013) Guideline for the prevention of acute nausea and vomiting due to antineoplastic medication in pediatric cancer patients. Pediatric Blood & Cancer 60(7), 10731082.10.1002/pbc.24508CrossRefGoogle ScholarPubMed
Dupuis, LL, Robinson, PD, Boodhan, S, et al. (2014) Guideline for the prevention and treatment of anticipatory nausea and vomiting due to chemotherapy in pediatric cancer patients. Pediatric Blood & Cancer 61(8), 15061512.10.1002/pbc.25063CrossRefGoogle ScholarPubMed
Fadul, N, Kaur, G, Zhang, T, et al. (2007) Evaluation of the memorial delirium assessment scale (MDAS) for the screening of delirium by means of simulated cases by palliative care health professionals. Supportive Care in Cancer 15(11), 12711276.10.1007/s00520-007-0247-6CrossRefGoogle ScholarPubMed
Traube, C, Silver, G, Kearney, J, et al. (2014a) Cornell assessment of pediatric delirium: A valid, rapid, observational tool for screening delirium in the PICU. Critical Care Medicine 42(3), 656663.10.1097/CCM.0b013e3182a66b76CrossRefGoogle Scholar
Traube, C, Augenstein, J, Greenwald, B, et al. (2014b) Neuroblastoma and pediatric delirium: A case series. Pediatric Blood & Cancer 61(6), 11211123.10.1002/pbc.24917CrossRefGoogle Scholar
Traube, C, Ariagno, S, Thau, F, et al. (2017a) Delirium in hospitalized children with cancer: Incidence and associated risk factors. The Journal of Pediatrics 191, 212217.10.1016/j.jpeds.2017.08.038CrossRefGoogle Scholar
Traube, C, Silver, G, Gerber, LM, et al. (2017b) Delirium and mortality in critically Ill children: Epidemiology and outcomes of pediatric delirium. Critical Care Medicine 45(5), 891898.10.1097/CCM.0000000000002324CrossRefGoogle Scholar
Winsnes, K, Sochacki, P, Eriksson, C, et al. (2019) Delirium in the pediatric hematology, oncology, and bone marrow transplant population. Pediatric Blood & Cancer 66(6), e27640.10.1002/pbc.27640CrossRefGoogle ScholarPubMed