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Home environment of 11-year-old children born to parents with schizophrenia or bipolar disorder – a controlled, 4-year follow-up study: The Danish High Risk and Resilience Study – VIA 11

Published online by Cambridge University Press:  25 November 2021

Mette Falkenberg Krantz Open the ORCID record for Mette Falkenberg Krantz [Opens in a new window] ,
Carsten Hjorthøj Open the ORCID record for Carsten Hjorthøj [Opens in a new window] ,
Julie Marie Brandt ,
Åsa Kremer Prøsch ,
Sinnika Birkehøj Rohd ,
Martin Wilms ,
Lotte Veddum ,
Nanna Lawaetz Steffensen ,
Christina Bruun Knudsen  and
Anna Krogh Andreasen
...Show all authors
Mette Falkenberg Krantz*
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark University of Copenhagen – Faculty of Health and Medical Sciences, Institute of Clinical Medicine, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Carsten Hjorthøj
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark Department of Public Health, Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark
Julie Marie Brandt
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark University of Copenhagen – Faculty of Health and Medical Sciences, Institute of Clinical Medicine, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Åsa Kremer Prøsch
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Sinnika Birkehøj Rohd
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Martin Wilms
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Lotte Veddum
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Nanna Lawaetz Steffensen
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Christina Bruun Knudsen
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Anna Krogh Andreasen
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Henriette Stadsgaard
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Nicoline Hemager
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark Research Unit at Child and Adolescent Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen, Denmark
Birgitte Klee Burton
Affiliation:
Research Unit at Child and Adolescent Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen, Denmark
Maja Gregersen
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark University of Copenhagen – Faculty of Health and Medical Sciences, Institute of Clinical Medicine, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Anne Søndergaard
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark University of Copenhagen – Faculty of Health and Medical Sciences, Institute of Clinical Medicine, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Aja Greve
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Ditte Lou Gantriis
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark
Marianne Melau
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark University of Copenhagen – Faculty of Health and Medical Sciences, Institute of Clinical Medicine, Copenhagen, Denmark Research Unit at Child and Adolescent Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen, Denmark
Jessica Ohland
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Preben Bo Mortensen
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark National Center for Register-based Research, Aarhus University, Aarhus, Denmark
Vibeke Bliksted
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Ole Mors
Affiliation:
iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark The Psychosis Research Unit, Aarhus University Hospital – Psychiatry, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health and Medical Services, Aarhus University, Aarhus, Denmark
Anne A. E. Thorup
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark University of Copenhagen – Faculty of Health and Medical Sciences, Institute of Clinical Medicine, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark Research Unit at Child and Adolescent Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen, Denmark
Merete Nordentoft
Affiliation:
CORE- Copenhagen Research Center for Mental Health, Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark University of Copenhagen – Faculty of Health and Medical Sciences, Institute of Clinical Medicine, Copenhagen, Denmark iPSYCH -The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
*
Author for correspondence: Mette Falkenberg Krantz, E-mail: Mette.Falkenberg.Krantz@regionh.dk
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Abstract

Background

The home environment has a major impact on child development. Parental severe mental illness can pose a challenge to the home environment of a child. We aimed to examine the home environment of children of parents with schizophrenia or bipolar disorder and controls longitudinally through at-home assessments.

Methods

Assessments were conducted within The Danish High Risk and Resilience Study, a nationwide multi-center cohort study of children of parents with schizophrenia or bipolar disorder and population-based controls. The level of at-home stimulation and support was measured at age 7 (N = 508 children) and age 11 (N = 430 children) with the semi-structured HOME Inventory. Results from the 11-year follow-up study were analyzed and compared with 7-year baseline results to examine change across groups.

Results

At age 11, children of parents with schizophrenia and bipolar disorder had lower levels of stimulation and support than controls (mean (s.d.) = 46.16 (5.56), 46.87 (5.34) and 49.25 (4.37) respectively, p < 0.001). A higher proportion of children with parental schizophrenia or bipolar disorder lived in inadequate home environments at age 11, compared with controls (N (%) = 24 (15.0), 12 (12.2) and 6 (3.5) respectively, p < 0.003). The changes in home environment scores did not differ across groups from age 7 to age 11.

Conclusions

Assessed longitudinally from the children's age of 7 to 11, children of parents with schizophrenia or bipolar disorder had lower levels of stimulation and support in their homes than controls. Integrated support which can target practical, economic, social and health issues to improve the home environment is indicated.

Keywords

Home environmentschizophreniabipolaroffspring
Type
Original Article
Information
Psychological Medicine , Volume 53 , Issue 6 , April 2023 , pp. 2563 - 2573
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Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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