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Molecular interactions and structure as analysed by fluorescence relaxation spectroscopy

Published online by Cambridge University Press:  17 March 2009

Rudolf Rigler  and
Måns Ehrenberg
Rudolf Rigler
Affiliation:
Institute for Cell Research, Medical Nobel Institute, Karolinska Institutet, Stockholm, Sweden
Måns Ehrenberg
Affiliation:
Institute for Cell Research, Medical Nobel Institute, Karolinska Institutet, Stockholm, Sweden
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Extract

Spectroscopic probes have become powerful tools in analysing the correlation between structure and function of biological macromolecules. Though these spectral methods cannot give as circumstantial information about the anatomy of a biological structure as, for example, X-ray diffraction they can provide information on physical properties at defined loci in a macromolecule which are not accessible by other techniques. Most important, spectroscopic studies have provided means to study the dynamics of structural changes and interactions in time domains spanning from nanoseconds and less up to infinite time.

Type
Research Article
Information
Quarterly Reviews of Biophysics , Volume 6 , Issue 2 , May 1973 , pp. 139 - 199
Copyright
Copyright © Cambridge University Press 1973

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