Hostname: page-component-848d4c4894-2pzkn Total loading time: 0 Render date: 2024-05-12T06:22:25.668Z Has data issue: false hasContentIssue false

Mortality Rates Associated With Multidrug-Resistant Acinetobacter baumannii Infection in Surgical Intensive Care Units

Published online by Cambridge University Press:  02 January 2015

Titus L. Daniels*
Affiliation:
Department of Medicine, Division of Infectious Diseases, Nashville, Tennessee
Stephen Deppen
Affiliation:
Vanderbilt University School of Medicine, and the Vanderbilt University Medical Center Department of Accreditation and Standards, Nashville, Tennessee
Patrick G. Arbogast
Affiliation:
Departments of Biostatistics, Nashville, Tennessee Preventive Medicine, Nashville, Tennessee
Marie R. Griffin
Affiliation:
Departments of Biostatistics, Nashville, Tennessee Preventive Medicine, Nashville, Tennessee
William Schaffner
Affiliation:
Department of Medicine, Division of Infectious Diseases, Nashville, Tennessee Departments of Biostatistics, Nashville, Tennessee Preventive Medicine, Nashville, Tennessee
Thomas R. Talbot
Affiliation:
Department of Medicine, Division of Infectious Diseases, Nashville, Tennessee Departments of Biostatistics, Nashville, Tennessee Preventive Medicine, Nashville, Tennessee
*
Vanderbilt University, Division of Infectious Diseases, A-2200 MCN, 1161 21st Ave. S, Nashville, TN 37232 (titus.daniels@vanderbilt.edu)

Abstract

A retrospective, propensity-matched cohort study was conducted to determine the mortality rate in patients with healthcare-associated infection (HAI) due to multidrug-resistant (MDR) Acinetobacter baumannii. The 28-day mortality rate for patients with MDR A. baumannii HAI was not significantly different than that for patients with non-MDR A. baumannii HAI. The median length of hospital stay before diagnosis of HAI was 4.5 days longer for patients with MDR A. baumannii infection than for patients with non-MDR A. baumannii infection (P <.001).

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Ayan, M, Durmaz, R, Aktas, E, Durmaz, B. Bacteriological, clinical and epidemiological characteristics of hospital-acquired Acinetobacter baumannii infection in a teaching hospital. J Hosp Infect 2003;54:3945.CrossRefGoogle ScholarPubMed
2.Paul, M, Weinberger, M, Siegman-Igra, Y, et al.Acinetobacter baumannii: emergence and spread in Israeli hospitals 1997-2002. J Hosp Infect 2005;60:256260.CrossRefGoogle ScholarPubMed
3.Go, ES, Urban, C, Burns, J, et al.Clinical and molecular epidemiology of Acinetobacter infections sensitive only to polymyxin B and sulbactam. Lancet 1994;344:13291332.CrossRefGoogle ScholarPubMed
4.Karlowsky, JA, Draghi, DC, Jones, ME, Thornsberry, C, Friedland, IR, Sahm, DESurveillance for antimicrobial susceptibility among clinical isolates of Pseudomonas aeruginosa and Acinetobacter baumannii from hospitalized patients in the United States, 1998 to 2001. Antimicrob Agents Chemother 2003;47:16811688.Google Scholar
5.Horan, TC, Gaynes, RP. Surveillance of nosocomial infections. In: Mayhall, CG, ed. Hospital Epidemiology and Infection Control. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2004:16591702.Google Scholar
6. Social Security Death Index Interactive Search. Vol. 2007. http:// www.RootsWeb.com. Accessed February 6, 2007.Google Scholar
7.Rosenbaum, P, Rubin, DB. The central role of the propensity score in observational studies for causal effects. Biometrika 1983;70:4155.Google Scholar
8.Lin, DY, Wei, LJ. Robust inference for the Cox proportional hazards model. I Am Stat Assoc 1989;84:10741078.CrossRefGoogle Scholar
9.Wilson, SJ, Knipe, CJ, Zieger, MJ, et al.Direct costs of multidrug-resistant Acinetobacter baumannii in the burn unit of a public teaching hospital. Am I Infect Control 2004;32:342344.CrossRefGoogle ScholarPubMed
10.Sunenshine, R, Wright, MO, Maragakis, L, et al.Multidrug-resistant Acinetobacter infection mortality rate and length of hospitalization. Emerg Infect Dis 2007;13:97103.CrossRefGoogle ScholarPubMed