Bottom-up Creation of an Artificial Cell Covered with the Adhesive Bacterionanofiber Protein AtaA

Kosaku Noba; Masahito Ishikawa; Atsuko Uyeda; Takayoshi Watanabe; Takahiro Hohsaka; Shogo Yoshimoto; Tomoaki Matsuura; Katsutoshi Hori

doi:10.26434/chemrxiv.9735161.v1

Biological and Medicinal Chemistry

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Bottom-up Creation of an Artificial Cell Covered with the Adhesive Bacterionanofiber Protein AtaA

28 August 2019, Version 1

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This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.

Abstract

This study demonstrates the bottom-up creation of an artificial cell which carries an active enzyme inside the cell and exhibit adhesive function to both hydrophobic and hydrophilic surfaces using AtaA, the adhesive bacterionanofiber protein from Acinetobacter sp. Tol 5, chemically coupled to the lipid membrane of the artificial cell.

Keywords

artificial cells

bottom-up synthetic biology

SNAP-tag

liposomes

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Bottom-up Creation of an Artificial Cell Covered with the Adhesive Bacterionanofiber Protein AtaA

Kosaku Noba, Masahito Ishikawa, Atsuko Uyeda, Takayoshi Watanabe, Takahiro Hohsaka, Shogo Yoshimoto, Tomoaki Matsuura, Katsutoshi Hori journal article

Journal of the American Chemical Society , Volume 141, Issue 48

Online publication date: Nov 07, 2019

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Aug 28, 2019 Version 1

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The content is available under CC BY NC ND 4.0

DOI

10.26434/chemrxiv.9735161.v1

Author’s competing interest statement

no conflict of interest

Bottom-up Creation of an Artificial Cell Covered with the Adhesive Bacterionanofiber Protein AtaA

Authors

Abstract

Keywords

Supplementary materials

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Now Published

Version History

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DOI

Author’s competing interest statement

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