How to Submit
Browse
Events
Communities
About

Superelectrophilic Aluminum(III)-Ion Pairs Promote a Distinct Reaction Path for Carbonyl-Olefin Metathesis of Medium-Sized Rings

30 September 2019, Version 1
Working Paper
This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.

Abstract

We describe the development of a new catalyst system for carbonyl-olefin ring-closing metathesis reactions that relies on Lewis acidic superelectrophiles and significantly expands the current scope of this transformation to medium-sized rings.
Importantly, these superelectrophiles are shown to promote carbonyl-olefin metathesis via a distinct and unprecedented mechanism.

Keywords

carbonyl-olefin metathesis, Lewis acid superelectrophiles

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting and Discussion Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Now Published

Superelectrophilic aluminium(iii)–ion pairs promote a distinct reaction path for carbonyl–olefin ring-closing metathesis [opens in a new tab]
Ashlee J. Davis, Rebecca B. Watson, Daniel J. Nasrallah, Jessica L. Gomez-Lopez, Corinna S. Schindler journal article
Nature Catalysis , Volume 3, Issue 10
Online publication date: Sep 21, 2020

Version History

Sep 30, 2019 Version 1

Metrics

5,380
1,525
5
Views
Downloads

License

CC logo
CC
BY logo
BY
NC logo
NC
ND logo
ND
The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv.9911783.v1
D O I: 10.26434/chemrxiv.9911783.v1 [opens in a new tab]

Funding

We thank the NIH/National Institute of General Medical Sci-ences (R01-GM118644), the Alfred P. Sloan Foundation, the David and Lucile Packard Foundation and the Camille and Hen-ry Dreyfus Foundation for financial support. R.B.W. thanks the National Science Foundation for a predoctoral fellowship. J.L.G.-L. thanks CONACyT for a postdoctoral fellowship.

Author’s competing interest statement

No conflict of interest

Share