How to Submit
Browse
Events
Communities
About

On the reactions of aryl and vinyl triflates with [Ni(COD)(dppf)]

26 May 2022, Version 1
Working Paper
This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.

Abstract

We report the experimental and computational investigations of the reactions of aryl and vinyl triflates with a model nickel(0) complex. Oxidative addition rates decrease in the order naphthyl > vinyl > phenyl, although 4-acetylphenyl triflate reacts most quickly due to favourable ketone coordination. Two possible reaction mechanisms are explored using DFT calculations.

Keywords

nickel catalysis
cross-coupling
oxidative addition

Supplementary materials

Title
Description
Actions
Title
Kinetic Data
Description
Kinetic Data
Actions
Title
Supporting Information
Description
Supporting Information
Actions
Title
DFT Coordinates
Description
DFT Coordinates
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting and Discussion Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

May 26, 2022 Version 1

Metrics

1,779
764
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
NC logo
NC
The content is available under CC BY NC 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2022-g8ng1
D O I: 10.26434/chemrxiv-2022-g8ng1 [opens in a new tab]

Funding

AstraZeneca
Engineering and Physical Sciences Research Council
EP/R512114/1

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share