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Methyl chlorothioformate as a convenient reagent for the thionoesters synthesis

24 September 2024, Version 1
Working Paper
This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.

Abstract

The perspective reagent for introducing methyl thionoester function into organic molecules is proposed. The scalable procedure for the reagent production is elaborated. The simple synthetic sequence based on the reaction of magnesium organic compounds and the proposed reagent for synthesizing diverse thionoesters is recommended. The reasons for metal selection are explained. The potential of the reaction, its advantages, simplicity, convenience, and effectiveness are demonstrated and discussed.

Keywords

tionoesters
magnesium organic compounds
methyl chlorothioformate
functional group

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Version History

Sep 24, 2024 Version 1

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The content is available under CC BY NC ND 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2024-s379b
D O I: 10.26434/chemrxiv-2024-s379b [opens in a new tab]

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

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