How to Submit
Browse
Events
Communities
About

Intermolecular Formal [8+3] Cycloaddition of Azaheptafulvene with Bicyclo[1.1.0]butanes Promoted by Lewis Acids

01 October 2024, Version 1
Working Paper
This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.

Abstract

Azaheptafulvenes reacting with bicyclo[1.1.0]butanes (BCBs) through FeCl3 or Sc(OTf)3-promoted formal [8+3] cycloaddition reactions to furnish Nitrogen-containing polycyclic compounds has been developed for the first time. This new reaction tolerated a wide range of azaheptafulvenes and BCBs. Furthermore, the amplification experiments and synthetic transformations of the cycloaddition compounds further highlighted its practicality.

Keywords

Azaheptafulvene
bicyclo[1.1.0]butane
[8+3] cycloaddition reaction
polycyclic compound

Supplementary materials

Title
Description
Actions
Title
Intermolecular Formal [8+3] Cycloaddition of Azaheptafulvene with Bicyclo[1.1.0]butanes Promoted by Lewis Acids
Description
Azaheptafulvenes reacting with bicyclo[1.1.0]butanes (BCBs) through FeCl3 or Sc(OTf)3-promoted formal [8+3] cycloaddition reactions to furnish Nitrogen-containing polycyclic compounds has been developed for the first time. This new reaction tolerated a wide range of azaheptafulvenes and BCBs. Furthermore, the amplification experiments and synthetic transformations of the cycloaddition compounds further highlighted its practicality.
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting and Discussion Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Oct 01, 2024 Version 1

Metrics

1,288
842
1
Views
Downloads

License

CC logo
CC
BY logo
BY
The content is available under CC BY 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2024-02ctf
D O I: 10.26434/chemrxiv-2024-02ctf [opens in a new tab]

Funding

National Natural Science Foundation of China
No. 22101188
National Natural Science Foundation of China
No. 22461036

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share