Cobaltaelectro-Catalyzed C-H Acyloxylation of Aromatic and Vinylic Amide Derivatives at Room Temperature

Herein, a mild and efficient cobalt-catalyzed electrochemical method for the C–H acyloxylation of aromatic and vinylic amides is reported. The 8-aminoquinoline directing group facilitates selective (ortho-)acyloxylation under electrochemical conditions at room temperature without the need for additional redox reagents. This sustainable protocol exhibits broad functional group tolerance and provides access to a wide range of acyloxylated amide derivatives using readily available carboxylic acids. The electrochemical approach avoids stoichiometric oxidants, generating only hydrogen as the byproduct, and thus offers a valuable alternative to traditional C–H functionalization strategies.