Abstract
Cyclic Voltammetry was used to determine the electrochemical behavior of untreated and carbonized avocado seeds to evaluate their interaction with acetaminophen. Fresh avocado seeds were manually peeled, sliced, and processed by thermal carbonization at 816 °C. A blank electrolyte of 0.1M KCl and acetaminophen standards prepared as 0.001M acetaminophen in 0.1M KCl were used to construct calibration curves that showed excellent linearity and validating the precise acetaminophen quantification analysis. Electrochemical measurements were performed using CV with a glassy carbon working electrode, platinum counter electrode, and Ag/AgCl reference electrode over a –1000mV to +1000 potential window at a scan rate of mV s⁻¹, were the solutions and calibration standards were analyzed under identical conditions to evaluate redox behavior and potential adsorption effects. The seed samples containing isopropanol generated inherent redox activity, confirming the presence of electroactive components. When exposed to acetaminophen, the seed samples produced a marked reduction in anodic peak current due to a partial adsorption of 35.05%. The results suggest that redox peaks highlight the ability of the avocado seed to retain pharmaceutical molecules with promising sustainable materials for electrochemical sensing and analytical applications.



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