How to Submit
Browse
Events
Communities
About

Boron Heterocycles via Direct Activation of Nitriles & Carbodiimides by alpha-Heteroboronates

13 January 2026, Version 1
Working Paper
This content is an early or alternative research output and has not been peer-reviewed by Cambridge University Press at the time of posting.

Abstract

Boron heterocycles can be formed at ambient temperature through the reaction of alpha-thio or alpha-amino boronates with nitriles or carbodiiimides. The chemistry can be applied to a wide range of unactivated nitriles. A range of amino acid and peptide analogues containing novel boron heterocycles were generated using these reactions.

Keywords

Boron
Nitriles
Heterocycles
Frustrated Lewis Pairs
Sulfur
Nitrogen

Supplementary materials

Title
Description
Actions
Title
Supporting Information
Description
Experimental procedures and characterisation data for all compounds, and 1H/13C/11B/19F NMR spectra for novel compounds.
Actions

Comments

Comments are not moderated before they are posted, but they can be removed by the site moderators if they are found to be in contravention of our Commenting and Discussion Policy [opens in a new tab] - please read this policy before you post. Comments should be used for scholarly discussion of the content in question. You can find more information about how to use the commenting feature here [opens in a new tab] .
This site is protected by reCAPTCHA and the Google Privacy Policy [opens in a new tab] and Terms of Service [opens in a new tab] apply.

Version History

Jan 13, 2026 Version 1

Metrics

1,300
268
0
Views
Downloads
Citations

License

CC logo
CC
BY logo
BY
The content is available under CC BY 4.0 [opens in a new tab]

DOI

10.26434/chemrxiv-2026-x44db
D O I: 10.26434/chemrxiv-2026-x44db [opens in a new tab]

Funding

Engineering and Physical Sciences Research Council
EP/T030488/1
Engineering and Physical Sciences Research Council
EP/T030658/1
Engineering and Physical Sciences Research Council
EP/T517628/1
Engineering and Physical Sciences Research Council
EP/N509577/1

Author’s competing interest statement

The author(s) have declared they have no conflict of interest with regard to this content

Ethics

The author(s) have declared ethics committee/IRB approval is not relevant to this content

Share